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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001278734.2 → NP_001265663.1 neurotrophin receptor-interacting factor homolog isoform d
Status: REVIEWED
- Description
- Transcript Variant: This variant (ZNF274d) has an additional segment in the 5' region, which results in a downstream translation start codon, compared to variant ZNF274c. The resulting isoform (d) has a shorter N-terminus and contains only one KRAB A domain, compared to isoform c.
- Source sequence(s)
-
BC009763, CA942346, DC362701, DC366107
- Consensus CDS
-
CCDS74475.1
- UniProtKB/TrEMBL
-
A0A0A0MR47
- Related
- ENSP00000321209.5, ENST00000326804.8
- Conserved Domains (8) summary
-
- smart00431
Location:115 → 227
- SCAN; leucine rich region
- smart00349
Location:245 → 285
- KRAB; krueppel associated box
- COG5048
Location:347 → 599
- COG5048; FOG: Zn-finger [General function prediction only]
- sd00017
Location:523 → 543
- ZF_C2H2; C2H2 Zn finger [structural motif]
- pfam00096
Location:549 → 571
- zf-C2H2; Zinc finger, C2H2 type
- pfam01352
Location:245 → 284
- KRAB; KRAB box
- pfam02023
Location:115 → 203
- SCAN; SCAN domain
- pfam13465
Location:563 → 588
- zf-H2C2_2; Zinc-finger double domain
-
NM_016324.4 → NP_057408.2 neurotrophin receptor-interacting factor homolog isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (ZNF274b) lacks three consecutive exons in the 5' region, which results in a downstream translation start codon, compared to variant ZNF274c. The resulting isoform (b) has a shorter N-terminus and contains only one KRAB A domain, compared to isoform c.
- Source sequence(s)
-
AK222855, BC009763, CA942346, DC366107
- Consensus CDS
-
CCDS74476.1
- UniProtKB/Swiss-Prot
-
Q96GC6
- Related
- ENSP00000409872.3, ENST00000424679.6
- Conserved Domains (6) summary
-
- COG5048
Location:284 → 536
- COG5048; FOG: Zn-finger [General function prediction only]
- sd00017
Location:460 → 480
- ZF_C2H2; C2H2 Zn finger [structural motif]
- pfam00096
Location:486 → 508
- zf-C2H2; Zinc finger, C2H2 type
- pfam01352
Location:181 → 222
- KRAB; KRAB box
- pfam02023
Location:52 → 138
- SCAN; SCAN domain
- pfam13465
Location:500 → 525
- zf-H2C2_2; Zinc-finger double domain
-
NM_016325.4 → NP_057409.1 neurotrophin receptor-interacting factor homolog isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (ZNF274a) lacks one in-frame coding exon, compared to variant ZNF274c. The resulting isoform (a) lacks an internal segment, compared to isoform c. Like isoform c, isoform a contains two KRAB A domains.
- Source sequence(s)
-
AB029150, CA942346, DC366107
- Consensus CDS
-
CCDS74474.1
- UniProtKB/Swiss-Prot
-
Q96GC6
- Related
- ENSP00000321187.5, ENST00000345813.7
- Conserved Domains (8) summary
-
- smart00431
Location:125 → 237
- SCAN; leucine rich region
- smart00349
Location:255 → 295
- KRAB; krueppel associated box
- COG5048
Location:357 → 612
- COG5048; FOG: Zn-finger [General function prediction only]
- sd00017
Location:533 → 553
- ZF_C2H2; C2H2 Zn finger [structural motif]
- pfam00096
Location:559 → 581
- zf-C2H2; Zinc finger, C2H2 type
- pfam01352
Location:14 → 53
- KRAB; KRAB box
- pfam02023
Location:125 → 213
- SCAN; SCAN domain
- pfam13465
Location:573 → 598
- zf-H2C2_2; Zinc-finger double domain
-
NM_133502.3 → NP_598009.1 neurotrophin receptor-interacting factor homolog isoform c
Status: REVIEWED
- Description
- Transcript Variant: This variant (ZNF274c) encodes the longest isoform (c). Isoform c contains two KRAB A domains.
- Source sequence(s)
-
AB029150, BC009763, CA942346, DC366107
- Consensus CDS
-
CCDS74473.1
- UniProtKB/Swiss-Prot
- Q53XU4, Q6MZG1, Q8WY37, Q8WY38, Q92969, Q96GC6, Q9UII0, Q9UII1
- Related
- ENSP00000484810.1, ENST00000617501.5
- Conserved Domains (8) summary
-
- smart00431
Location:157 → 269
- SCAN; leucine rich region
- smart00349
Location:14 → 73
- KRAB; krueppel associated box
- COG5048
Location:389 → 644
- COG5048; FOG: Zn-finger [General function prediction only]
- sd00017
Location:565 → 585
- ZF_C2H2; C2H2 Zn finger [structural motif]
- pfam00096
Location:591 → 613
- zf-C2H2; Zinc finger, C2H2 type
- pfam01352
Location:14 → 53
- KRAB; KRAB box
- pfam02023
Location:157 → 245
- SCAN; SCAN domain
- pfam13465
Location:605 → 630
- zf-H2C2_2; Zinc-finger double domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000019.10 Reference GRCh38.p14 Primary Assembly
- Range
-
58183061..58213562
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047438078.1 → XP_047294034.1 neurotrophin receptor-interacting factor homolog isoform X4
- UniProtKB/TrEMBL
-
B4DMH6
-
XM_011526327.2 → XP_011524629.1 neurotrophin receptor-interacting factor homolog isoform X2
- UniProtKB/Swiss-Prot
-
Q96GC6
- Conserved Domains (6) summary
-
- COG5048
Location:284 → 536
- COG5048; FOG: Zn-finger [General function prediction only]
- sd00017
Location:460 → 480
- ZF_C2H2; C2H2 Zn finger [structural motif]
- pfam00096
Location:486 → 508
- zf-C2H2; Zinc finger, C2H2 type
- pfam01352
Location:181 → 222
- KRAB; KRAB box
- pfam02023
Location:52 → 138
- SCAN; SCAN domain
- pfam13465
Location:500 → 525
- zf-H2C2_2; Zinc-finger double domain
-
XM_047438076.1 → XP_047294032.1 neurotrophin receptor-interacting factor homolog isoform X1
- UniProtKB/Swiss-Prot
- Q53XU4, Q6MZG1, Q8WY37, Q8WY38, Q92969, Q96GC6, Q9UII0, Q9UII1
-
XM_017026175.2 → XP_016881664.1 neurotrophin receptor-interacting factor homolog isoform X4
- UniProtKB/TrEMBL
-
B4DMH6
-
XM_047438075.1 → XP_047294031.1 neurotrophin receptor-interacting factor homolog isoform X1
- UniProtKB/Swiss-Prot
- Q53XU4, Q6MZG1, Q8WY37, Q8WY38, Q92969, Q96GC6, Q9UII0, Q9UII1
- Related
- ENSP00000478533.1, ENST00000610905.4
-
XM_047438077.1 → XP_047294033.1 neurotrophin receptor-interacting factor homolog isoform X2
-
XM_011526328.3 → XP_011524630.1 neurotrophin receptor-interacting factor homolog isoform X3
- Conserved Domains (3) summary
-
- sd00017
Location:250 → 270
- ZF_C2H2; C2H2 Zn finger [structural motif]
- pfam00096
Location:276 → 298
- zf-C2H2; Zinc finger, C2H2 type
- pfam13465
Location:290 → 315
- zf-H2C2_2; Zinc-finger double domain
RNA
-
XR_007066543.1 RNA Sequence
-
XR_001753589.3 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060943.1 Alternate T2T-CHM13v2.0
- Range
-
61276790..61310024
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054319567.1 → XP_054175542.1 neurotrophin receptor-interacting factor homolog isoform X1
-
XM_054319572.1 → XP_054175547.1 neurotrophin receptor-interacting factor homolog isoform X4
- UniProtKB/TrEMBL
-
B4DMH6
-
XM_054319569.1 → XP_054175544.1 neurotrophin receptor-interacting factor homolog isoform X2
-
XM_054319568.1 → XP_054175543.1 neurotrophin receptor-interacting factor homolog isoform X1
-
XM_054319570.1 → XP_054175545.1 neurotrophin receptor-interacting factor homolog isoform X2
-
XM_054319571.1 → XP_054175546.1 neurotrophin receptor-interacting factor homolog isoform X3
RNA
-
XR_008485067.1 RNA Sequence
-
XR_008485068.1 RNA Sequence
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001278735.1: Suppressed sequence
- Description
- NM_001278735.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.