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ARPP21 cAMP regulated phosphoprotein 21 [ Homo sapiens (human) ]

Gene ID: 10777, updated on 5-Aug-2018

Summary

Official Symbol
ARPP21provided by HGNC
Official Full Name
cAMP regulated phosphoprotein 21provided by HGNC
Primary source
HGNC:HGNC:16968
See related
Ensembl:ENSG00000172995 MIM:605488; Vega:OTTHUMG00000130795
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RCS; TARPP; R3HDM3; ARPP-21
Summary
This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Expression
Biased expression in brain (RPKM 4.3) and esophagus (RPKM 0.1) See more
Orthologs

Genomic context

See ARPP21 in Genome Data Viewer
Location:
3p22.3
Exon count:
28
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (35639174..35798933)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (35680666..35835988)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928135 Neighboring gene keratin 8 pseudogene 18 Neighboring gene RNA, U6 small nuclear 243, pseudogene Neighboring gene microRNA 128-2 Neighboring gene ribosomal protein L36a pseudogene 17 Neighboring gene replication factor C 3 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
NHGRI GWA Catalog
Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ32997

Gene Ontology Provided by GOA

Function Evidence Code Pubs
calmodulin binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
cellular response to heat IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cAMP-regulated phosphoprotein 21
Names
R3H domain containing 3
cAMP regulated phosphoprotein 21kDa
cyclic AMP-regulated phosphoprotein, 21 kD
thymocyte cAMP-regulated phosphoprotein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_050660.1 RefSeqGene

    Range
    8184..160323
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001025068.1NP_001020239.1  cAMP-regulated phosphoprotein 21 isoform 2

    See identical proteins and their annotated locations for NP_001020239.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) uses two alternate 5' exons and an alternate 3' exon compared to variant 1. The resulting isoform (2) has a distinct and much shorter C-terminus compared to isoform 1. Variants 2, 3, 4, 5 and 7 all encode the same isoform (2).
    Source sequence(s)
    AC016943, AV718064
    Consensus CDS
    CCDS43063.1
    UniProtKB/Swiss-Prot
    Q9UBL0
    UniProtKB/TrEMBL
    A8K1F3
    Related
    ENSP00000417838.1, OTTHUMP00000208646, ENST00000474696.5, OTTHUMT00000341648
    Conserved Domains (1) summary
    pfam14134
    Location:2260
    DUF4301; Domain of unknown function (DUF4301)
  2. NM_001025069.1NP_001020240.1  cAMP-regulated phosphoprotein 21 isoform 2

    See identical proteins and their annotated locations for NP_001020240.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) uses two alternate 5' exons and an alternate 3' exon compared to variant 1. The resulting isoform (2) has a distinct and much shorter C-terminus compared to isoform 1. Variants 2, 3, 4, 5 and 7 all encode the same isoform (2).
    Source sequence(s)
    AC016943, AK055064, AV718064
    Consensus CDS
    CCDS43063.1
    UniProtKB/Swiss-Prot
    Q9UBL0
    UniProtKB/TrEMBL
    A8K1F3
    Related
    ENSP00000379742.2, OTTHUMP00000208638, ENST00000396482.6, OTTHUMT00000341612
    Conserved Domains (1) summary
    pfam14134
    Location:2260
    DUF4301; Domain of unknown function (DUF4301)
  3. NM_001267616.1NP_001254545.1  cAMP-regulated phosphoprotein 21 isoform 2

    See identical proteins and their annotated locations for NP_001254545.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' and 3' UTR, lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1. Variants 2, 3, 4, 5 and 7 all encode the same isoform (2).
    Source sequence(s)
    AC016943, BC036548, BC041385
    Consensus CDS
    CCDS43063.1
    UniProtKB/Swiss-Prot
    Q9UBL0
    UniProtKB/TrEMBL
    A8K1F3
    Related
    ENSP00000412411.1, OTTHUMP00000208636, ENST00000428373.5, OTTHUMT00000341610
    Conserved Domains (1) summary
    pfam14134
    Location:2260
    DUF4301; Domain of unknown function (DUF4301)
  4. NM_001267617.1NP_001254546.1  cAMP-regulated phosphoprotein 21 isoform 3

    See identical proteins and their annotated locations for NP_001254546.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) contains a distinct 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The resulting isoform (3) is shorter, compared to isoform 1.
    Source sequence(s)
    AC016943, BC036399, BU741999
    Consensus CDS
    CCDS58824.1
    UniProtKB/Swiss-Prot
    Q9UBL0
    Related
    ENSP00000405276.1, OTTHUMP00000208635, ENST00000444190.5, OTTHUMT00000341609
    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09726
    Location:222347
    Macoilin; Transmembrane protein
    cl25764
    Location:553727
    PAT1; Topoisomerase II-associated protein PAT1
    cl26464
    Location:373640
    Atrophin-1; Atrophin-1 family
  5. NM_001267618.1NP_001254547.1  cAMP-regulated phosphoprotein 21 isoform 2

    See identical proteins and their annotated locations for NP_001254547.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' and 3' UTR, lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1. Variants 2, 3, 4, 5 and 7 all encode the same isoform (2).
    Source sequence(s)
    AC016943, AK289649, BC036548, DA275579
    Consensus CDS
    CCDS43063.1
    UniProtKB/Swiss-Prot
    Q9UBL0
    UniProtKB/TrEMBL
    A8K0T4, A8K1F3
    Related
    ENSP00000390151.1, OTTHUMP00000208637, ENST00000412048.5, OTTHUMT00000341611
    Conserved Domains (1) summary
    pfam14134
    Location:2260
    DUF4301; Domain of unknown function (DUF4301)
  6. NM_001267619.1NP_001254548.1  cAMP-regulated phosphoprotein 21 isoform 4

    See identical proteins and their annotated locations for NP_001254548.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) has a shorter 5' UTR and lacks two in-frame exons in the central coding region, compared to variant 1. The resulting isoform (4) is shorter, compared to isoform 1.
    Source sequence(s)
    AC016943, AK294484, BU741999
    Consensus CDS
    CCDS58823.1
    UniProtKB/Swiss-Prot
    Q9UBL0
    Related
    ENSP00000412326.1, OTTHUMP00000208639, ENST00000417925.5, OTTHUMT00000341613
    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  7. NM_016300.4NP_057384.2  cAMP-regulated phosphoprotein 21 isoform 1

    See identical proteins and their annotated locations for NP_057384.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC016943, AC104308, BC051828
    Consensus CDS
    CCDS2661.1
    UniProtKB/Swiss-Prot
    Q9UBL0
    Related
    ENSP00000187397.4, OTTHUMP00000161358, ENST00000187397.8, OTTHUMT00000253334
    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam11235
    Location:601773
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12752
    Location:245300
    SUZ; SUZ domain
  8. NM_198399.1NP_938409.1  cAMP-regulated phosphoprotein 21 isoform 2

    See identical proteins and their annotated locations for NP_938409.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate 5' exon and an alternate 3' exon compared to variant 1. The resulting isoform (2) has a distinct and much shorter C-terminus compared to isoform 1. Variants 2, 3, 4, 5 and 7 all encode the same isoform (2).
    Source sequence(s)
    AC016943, BC017805, BC036548
    Consensus CDS
    CCDS43063.1
    UniProtKB/Swiss-Prot
    Q9UBL0
    UniProtKB/TrEMBL
    A8K1F3
    Related
    ENSP00000379741.2, OTTHUMP00000208640, ENST00000396481.6, OTTHUMT00000341615

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p12 Primary Assembly

    Range
    35639174..35798933
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017005580.2XP_016861069.1  cAMP-regulated phosphoprotein 21 isoform X2

    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam10631
    Location:562667
    DUF2477; Protein of unknown function (DUF2477)
    pfam11235
    Location:636808
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12752
    Location:245300
    SUZ; SUZ domain
  2. XM_017005595.2XP_016861084.1  cAMP-regulated phosphoprotein 21 isoform X8

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  3. XM_017005592.2XP_016861081.1  cAMP-regulated phosphoprotein 21 isoform X8

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  4. XM_011533303.3XP_011531605.1  cAMP-regulated phosphoprotein 21 isoform X1

    See identical proteins and their annotated locations for XP_011531605.1

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:542826
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  5. XM_017005588.2XP_016861077.1  cAMP-regulated phosphoprotein 21 isoform X6

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:521805
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  6. XM_017005598.2XP_016861087.1  cAMP-regulated phosphoprotein 21 isoform X10

    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  7. XM_017005605.2XP_016861094.1  cAMP-regulated phosphoprotein 21 isoform X12

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09726
    Location:222347
    Macoilin; Transmembrane protein
    cl25764
    Location:553727
    PAT1; Topoisomerase II-associated protein PAT1
    cl26464
    Location:373640
    Atrophin-1; Atrophin-1 family
  8. XM_011533299.3XP_011531601.1  cAMP-regulated phosphoprotein 21 isoform X1

    See identical proteins and their annotated locations for XP_011531601.1

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:542826
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  9. XM_017005576.2XP_016861065.1  cAMP-regulated phosphoprotein 21 isoform X2

    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam10631
    Location:562667
    DUF2477; Protein of unknown function (DUF2477)
    pfam11235
    Location:636808
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12752
    Location:245300
    SUZ; SUZ domain
  10. XM_017005579.2XP_016861068.1  cAMP-regulated phosphoprotein 21 isoform X3

    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam10631
    Location:562667
    DUF2477; Protein of unknown function (DUF2477)
    pfam11235
    Location:636808
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12752
    Location:245300
    SUZ; SUZ domain
  11. XM_017005582.2XP_016861071.1  cAMP-regulated phosphoprotein 21 isoform X4

  12. XM_017005584.2XP_016861073.1  cAMP-regulated phosphoprotein 21 isoform X5

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam10631
    Location:543648
    DUF2477; Protein of unknown function (DUF2477)
    pfam12752
    Location:245300
    SUZ; SUZ domain
  13. XM_017005585.2XP_016861074.1  cAMP-regulated phosphoprotein 21 isoform X6

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:521805
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  14. XM_017005591.2XP_016861080.1  cAMP-regulated phosphoprotein 21 isoform X7

    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  15. XM_017005596.2XP_016861085.1  cAMP-regulated phosphoprotein 21 isoform X9

    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  16. XM_017005597.2XP_016861086.1  cAMP-regulated phosphoprotein 21 isoform X10

    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  17. XM_017005599.2XP_016861088.1  cAMP-regulated phosphoprotein 21 isoform X11

    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  18. XM_017005602.2XP_016861091.1  cAMP-regulated phosphoprotein 21 isoform X12

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09726
    Location:222347
    Macoilin; Transmembrane protein
    cl25764
    Location:553727
    PAT1; Topoisomerase II-associated protein PAT1
    cl26464
    Location:373640
    Atrophin-1; Atrophin-1 family
  19. XM_017005610.2XP_016861099.1  cAMP-regulated phosphoprotein 21 isoform X15

  20. XM_017005612.2XP_016861101.1  cAMP-regulated phosphoprotein 21 isoform X15

  21. XM_024453324.1XP_024309092.1  cAMP-regulated phosphoprotein 21 isoform X14

    Conserved Domains (3) summary
    pfam09606
    Location:272556
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:232
    SUZ; SUZ domain
    cl25764
    Location:375512
    PAT1; Topoisomerase II-associated protein PAT1
  22. XM_017005607.2XP_016861096.1  cAMP-regulated phosphoprotein 21 isoform X13

  23. XM_017005593.2XP_016861082.1  cAMP-regulated phosphoprotein 21 isoform X8

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  24. XM_017005574.2XP_016861063.1  cAMP-regulated phosphoprotein 21 isoform X1

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:542826
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  25. XM_011533300.3XP_011531602.1  cAMP-regulated phosphoprotein 21 isoform X1

    See identical proteins and their annotated locations for XP_011531602.1

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:542826
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  26. XM_017005587.2XP_016861076.1  cAMP-regulated phosphoprotein 21 isoform X6

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:521805
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  27. XM_017005600.2XP_016861089.1  cAMP-regulated phosphoprotein 21 isoform X11

    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  28. XM_017005603.2XP_016861092.1  cAMP-regulated phosphoprotein 21 isoform X12

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09726
    Location:222347
    Macoilin; Transmembrane protein
    cl25764
    Location:553727
    PAT1; Topoisomerase II-associated protein PAT1
    cl26464
    Location:373640
    Atrophin-1; Atrophin-1 family
  29. XM_024453320.1XP_024309088.1  cAMP-regulated phosphoprotein 21 isoform X1

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:542826
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  30. XM_024453322.1XP_024309090.1  cAMP-regulated phosphoprotein 21 isoform X6

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:521805
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  31. XM_024453323.1XP_024309091.1  cAMP-regulated phosphoprotein 21 isoform X12

    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09726
    Location:222347
    Macoilin; Transmembrane protein
    cl25764
    Location:553727
    PAT1; Topoisomerase II-associated protein PAT1
    cl26464
    Location:373640
    Atrophin-1; Atrophin-1 family
  32. XM_017005575.2XP_016861064.1  cAMP-regulated phosphoprotein 21 isoform X1

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:542826
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  33. XM_017005581.2XP_016861070.1  cAMP-regulated phosphoprotein 21 isoform X3

    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam10631
    Location:562667
    DUF2477; Protein of unknown function (DUF2477)
    pfam11235
    Location:636808
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12752
    Location:245300
    SUZ; SUZ domain
  34. XM_017005590.2XP_016861079.1  cAMP-regulated phosphoprotein 21 isoform X6

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:521805
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  35. XM_017005594.1XP_016861083.1  cAMP-regulated phosphoprotein 21 isoform X8

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  36. XM_011533301.3XP_011531603.1  cAMP-regulated phosphoprotein 21 isoform X1

    See identical proteins and their annotated locations for XP_011531603.1

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:542826
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  37. XM_017005577.2XP_016861066.1  cAMP-regulated phosphoprotein 21 isoform X2

    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam10631
    Location:562667
    DUF2477; Protein of unknown function (DUF2477)
    pfam11235
    Location:636808
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12752
    Location:245300
    SUZ; SUZ domain
  38. XM_017005583.2XP_016861072.1  cAMP-regulated phosphoprotein 21 isoform X4

  39. XM_017005601.2XP_016861090.1  cAMP-regulated phosphoprotein 21 isoform X11

    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  40. XM_017005604.2XP_016861093.1  cAMP-regulated phosphoprotein 21 isoform X12

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09726
    Location:222347
    Macoilin; Transmembrane protein
    cl25764
    Location:553727
    PAT1; Topoisomerase II-associated protein PAT1
    cl26464
    Location:373640
    Atrophin-1; Atrophin-1 family
  41. XM_006712943.3XP_006713006.1  cAMP-regulated phosphoprotein 21 isoform X8

    See identical proteins and their annotated locations for XP_006713006.1

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (1) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
  42. XM_011533298.3XP_011531600.1  cAMP-regulated phosphoprotein 21 isoform X1

    See identical proteins and their annotated locations for XP_011531600.1

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:542826
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  43. XM_005264811.3XP_005264868.1  cAMP-regulated phosphoprotein 21 isoform X2

    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam10631
    Location:562667
    DUF2477; Protein of unknown function (DUF2477)
    pfam11235
    Location:636808
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam12752
    Location:245300
    SUZ; SUZ domain
  44. XM_017005586.2XP_016861075.1  cAMP-regulated phosphoprotein 21 isoform X6

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:521805
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  45. XM_006712944.3XP_006713007.1  cAMP-regulated phosphoprotein 21 isoform X12

    See identical proteins and their annotated locations for XP_006713007.1

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09726
    Location:222347
    Macoilin; Transmembrane protein
    cl25764
    Location:553727
    PAT1; Topoisomerase II-associated protein PAT1
    cl26464
    Location:373640
    Atrophin-1; Atrophin-1 family
  46. XM_011533302.3XP_011531604.1  cAMP-regulated phosphoprotein 21 isoform X1

    See identical proteins and their annotated locations for XP_011531604.1

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:542826
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  47. XM_017005589.2XP_016861078.1  cAMP-regulated phosphoprotein 21 isoform X6

    Conserved Domains (3) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09606
    Location:521805
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam12752
    Location:245300
    SUZ; SUZ domain
  48. XM_017005606.2XP_016861095.1  cAMP-regulated phosphoprotein 21 isoform X12

    UniProtKB/Swiss-Prot
    Q9UBL0
    Conserved Domains (4) summary
    cd02642
    Location:163224
    R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...
    pfam09726
    Location:222347
    Macoilin; Transmembrane protein
    cl25764
    Location:553727
    PAT1; Topoisomerase II-associated protein PAT1
    cl26464
    Location:373640
    Atrophin-1; Atrophin-1 family
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