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Ankrd1 ankyrin repeat domain 1 (cardiac muscle) [ Mus musculus (house mouse) ]

Gene ID: 107765, updated on 15-Apr-2019

Summary

Official Symbol
Ankrd1provided by MGI
Official Full Name
ankyrin repeat domain 1 (cardiac muscle)provided by MGI
Primary source
MGI:MGI:1097717
See related
Ensembl:ENSMUSG00000024803
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Alrp; CARP; Crap; MARP1
Expression
Restricted expression toward heart adult (RPKM 150.0) See more
Orthologs

Genomic context

See Ankrd1 in Genome Data Viewer
Location:
19; 19 C2
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (36111965..36119844, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (36186455..36194334, complement)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine (serotonin) receptor 7 Neighboring gene ribonuclease P/MRP 30 subunit Neighboring gene predicted gene, 32081 Neighboring gene predicted gene, 32027 Neighboring gene predicted gene, 46664

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding ISO
Inferred from Sequence Orthology
more info
 
R-SMAD binding ISO
Inferred from Sequence Orthology
more info
 
RNA polymerase II sequence-specific DNA-binding transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
histone deacetylase binding ISO
Inferred from Sequence Orthology
more info
 
p53 binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
titin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
titin binding IPI
Inferred from Physical Interaction
more info
PubMed 
titin binding ISO
Inferred from Sequence Orthology
more info
 
transcription coactivator activity ISO
Inferred from Sequence Orthology
more info
 
transcription corepressor activity IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cardiac muscle tissue morphogenesis ISO
Inferred from Sequence Orthology
more info
 
cellular response to drug IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to interleukin-1 ISO
Inferred from Sequence Orthology
more info
 
cellular response to lipopolysaccharide IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
 
cellular response to mechanical stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular response to transforming growth factor beta stimulus ISO
Inferred from Sequence Orthology
more info
 
cellular response to tumor necrosis factor ISO
Inferred from Sequence Orthology
more info
 
negative regulation of DNA biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of DNA damage response, signal transduction by p53 class mediator ISO
Inferred from Sequence Orthology
more info
 
positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein secretion ISO
Inferred from Sequence Orthology
more info
 
protein kinase C signaling IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
PubMed 
response to muscle stretch ISO
Inferred from Sequence Orthology
more info
 
skeletal muscle cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
skeletal muscle tissue development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
I band IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
I band IDA
Inferred from Direct Assay
more info
PubMed 
I band ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
fibrillar center ISO
Inferred from Sequence Orthology
more info
 
myofibril IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
ankyrin repeat domain-containing protein 1
Names
ankyrin-like repeat protein
cardiac ankyrin repeat protein
cardiac responsive adriamycin protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013468.3NP_038496.2  ankyrin repeat domain-containing protein 1

    See identical proteins and their annotated locations for NP_038496.2

    Status: VALIDATED

    Source sequence(s)
    AC119234
    Consensus CDS
    CCDS29771.1
    UniProtKB/Swiss-Prot
    Q9CR42
    Related
    ENSMUSP00000157960.1, ENSMUST00000237142.1
    Conserved Domains (4) summary
    cd00204
    Location:147272
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:157249
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:126172
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:188216
    ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

    Range
    36111965..36119844 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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