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Mrpl10 mitochondrial ribosomal protein L10 [ Mus musculus (house mouse) ]

Gene ID: 107732, updated on 30-Apr-2024

Summary

Official Symbol
Mrpl10provided by MGI
Official Full Name
mitochondrial ribosomal protein L10provided by MGI
Primary source
MGI:MGI:1333801
See related
Ensembl:ENSMUSG00000001445 AllianceGenome:MGI:1333801
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
L10mt; Rpml8; MRP-L8; 0610040E02Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to act upstream of or within ribosome biogenesis. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL10 (mitochondrial ribosomal protein L10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 100.8), kidney adult (RPKM 56.1) and 28 other tissues See more
Orthologs
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Genomic context

See Mrpl10 in Genome Data Viewer
Location:
11 D; 11 60.69 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (96932408..96940039)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (97041582..97049213)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene secernin 2 Neighboring gene leucine rich repeat containing 46 Neighboring gene predicted gene 11533 Neighboring gene STARR-positive B cell enhancer ABC_E909 Neighboring gene STARR-positive B cell enhancer ABC_E8445 Neighboring gene oxysterol binding protein-like 7 Neighboring gene predicted gene, 51917 Neighboring gene microRNA 8103

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC28763

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within ribosome biogenesis ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large ribosomal subunit protein uL10m
Names
39S ribosomal protein L10, mitochondrial
NP_001344736.1
NP_001344737.1
NP_080430.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001357807.2NP_001344736.1  large ribosomal subunit protein uL10m isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK150774, BF458354, BI989554, BY127904, CD561609
    Conserved Domains (1) summary
    cl00376
    Location:81158
    Ribosomal_L10_P0; Ribosomal protein L10 family; composed of the large subunit ribosomal protein called L10 in bacteria, P0 in eukaryotes, and L10e in archaea, as well as uncharacterized P0-like eukaryotic proteins. In all three kingdoms, L10 forms a tight complex with ...
  2. NM_001357808.2NP_001344737.1  large ribosomal subunit protein uL10m isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK150774, BF458354, BY127904, CD561609
    Conserved Domains (1) summary
    cd05797
    Location:1134
    Ribosomal_L10; Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein ...
  3. NM_026154.3NP_080430.1  large ribosomal subunit protein uL10m isoform 1 precursor

    See identical proteins and their annotated locations for NP_080430.1

    Status: VALIDATED

    Source sequence(s)
    AK150774, BF458354, CD561609
    Consensus CDS
    CCDS25312.1
    UniProtKB/Swiss-Prot
    Q3TBW2, Q9CQD2
    Related
    ENSMUSP00000001485.4, ENSMUST00000001485.10
    Conserved Domains (1) summary
    cd05797
    Location:81228
    Ribosomal_L10; Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    96932408..96940039
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)