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ZMYND11 zinc finger MYND-type containing 11 [ Homo sapiens (human) ]

Gene ID: 10771, updated on 1-Aug-2020

Summary

Official Symbol
ZMYND11provided by HGNC
Official Full Name
zinc finger MYND-type containing 11provided by HGNC
Primary source
HGNC:HGNC:16966
See related
Ensembl:ENSG00000015171 MIM:608668
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BS69; BRAM1; MRD30
Summary
The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in thyroid (RPKM 38.3), brain (RPKM 25.5) and 25 other tissues See more
Orthologs

Genomic context

See ZMYND11 in Genome Data Viewer
Location:
10p15.3
Exon count:
23
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (130088..254637)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (180405..300577)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene tubulin beta 8 class VIII Neighboring gene interleukin 9 receptor pseudogene 2 Neighboring gene RNA, 5S ribosomal pseudogene 297 Neighboring gene DEAD-box helicase 20 pseudogene 1 Neighboring gene uncharacterized LOC107984190 Neighboring gene uncharacterized LOC107984191 Neighboring gene RNA, 5S ribosomal pseudogene 298 Neighboring gene disco interacting protein 2 homolog C

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Mental retardation, autosomal dominant 30
MedGen: C4015167 OMIM: 616083 GeneReviews: Not available
Compare labs

Copy number response

Description
Copy number response
Triplosensitivity

No evidence available (Last evaluated (2018-03-28)

ClinGen Genome Curation PagePubMed
Haploinsufficency

Sufficient evidence for dosage pathogenicity (Last evaluated (2018-03-28)

ClinGen Genome Curation PagePubMed

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC111056

Gene Ontology Provided by GOA

Function Evidence Code Pubs
double-stranded DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
methylated histone binding IDA
Inferred from Direct Assay
more info
PubMed 
methylated histone binding ISS
Inferred from Sequence or Structural Similarity
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription corepressor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
zinc ion binding IDA
Inferred from Direct Assay
more info
PubMed 
zinc ion binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
chromatin organization IEA
Inferred from Electronic Annotation
more info
 
defense response to virus IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of I-kappaB kinase/NF-kappaB signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of JNK cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of extrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription, DNA-templated TAS
Traceable Author Statement
more info
PubMed 
regulation of transcription elongation from RNA polymerase II promoter ISS
Inferred from Sequence or Structural Similarity
more info
 
viral process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
chromosome IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger MYND domain-containing protein 11
Names
adenovirus 5 E1A-binding protein
bone morphogenetic protein receptor-associated molecule 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029960.1 RefSeqGene

    Range
    5001..125173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001202464.3NP_001189393.1  zinc finger MYND domain-containing protein 11 isoform c

    See identical proteins and their annotated locations for NP_001189393.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4), as well as variants 16-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73060.1
    UniProtKB/Swiss-Prot
    Q15326
    UniProtKB/TrEMBL
    Q5BJG6, Q5UGI2
    Related
    ENSP00000371020.5, ENST00000381607.8
    Conserved Domains (3) summary
    cd05841
    Location:218299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509544
    zf-MYND; MYND finger
  2. NM_001202465.3NP_001189394.1  zinc finger MYND domain-containing protein 11 isoform d

    See identical proteins and their annotated locations for NP_001189394.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5), as well as variant 23, encodes isoform d.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS55697.1
    UniProtKB/Swiss-Prot
    Q15326
    UniProtKB/TrEMBL
    Q5BJG6, Q5UGI2
    Related
    ENSP00000381050.3, ENST00000397959.7
    Conserved Domains (3) summary
    cd05841
    Location:187268
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:478513
    zf-MYND; MYND finger
    cl02556
    Location:95173
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  3. NM_001202466.3NP_001189395.1  zinc finger MYND domain-containing protein 11 isoform e

    See identical proteins and their annotated locations for NP_001189395.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6), as well as variant 24, encodes isoform e.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS73061.1
    UniProtKB/TrEMBL
    B7Z2J6, Q5BJG6, Q5UGI2
    Related
    ENSP00000309992.5, ENST00000309776.8
    Conserved Domains (3) summary
    cd05841
    Location:217298
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104203
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:508543
    zf-MYND; MYND finger
  4. NM_001202467.1NP_001189396.1  zinc finger MYND domain-containing protein 11 isoform f

    See identical proteins and their annotated locations for NP_001189396.1

    Status: REVIEWED

    Source sequence(s)
    AI244299, AL589988, BC034784, DB521520, DQ335454
    UniProtKB/Swiss-Prot
    Q15326
    Conserved Domains (2) summary
    cd05841
    Location:218299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
  5. NM_001202468.1NP_001189397.1  zinc finger MYND domain-containing protein 11 isoform g

    See identical proteins and their annotated locations for NP_001189397.1

    Status: REVIEWED

    Source sequence(s)
    AI244299, AL589988, BC034784, DB521520, DQ335455
    Consensus CDS
    CCDS55696.1
    UniProtKB/Swiss-Prot
    Q15326
    Related
    ENSP00000452959.1, ENST00000558098.4
    Conserved Domains (3) summary
    cd05841
    Location:272353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
  6. NM_001330057.3NP_001316986.1  zinc finger MYND domain-containing protein 11 isoform h

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variant 25, encodes isoform h.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS81436.1
    UniProtKB/TrEMBL
    J3QKD2
    Related
    ENSP00000487386.1, ENST00000627286.1
    Conserved Domains (4) summary
    cd05841
    Location:255336
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:141241
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:85128
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:546581
    zf-MYND; MYND finger
  7. NM_001370097.3NP_001357026.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 1 and 11-15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (4) summary
    cd05841
    Location:272353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563598
    zf-MYND; MYND finger
  8. NM_001370098.2NP_001357027.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variants 1, 10, and 12-15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (4) summary
    cd05841
    Location:272353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563598
    zf-MYND; MYND finger
  9. NM_001370099.2NP_001357028.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variants 1, 10, 11, and 13-15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Related
    ENSP00000371003.1, ENST00000381591.5
    Conserved Domains (4) summary
    cd05841
    Location:272353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563598
    zf-MYND; MYND finger
  10. NM_001370100.5NP_001357029.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variants 1, 10-12, 14, and 15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (4) summary
    cd05841
    Location:272353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563598
    zf-MYND; MYND finger
  11. NM_001370101.2NP_001357030.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 1, 10-13, and 15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (4) summary
    cd05841
    Location:272353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563598
    zf-MYND; MYND finger
  12. NM_001370102.2NP_001357031.1  zinc finger MYND domain-containing protein 11 isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variants 1 and 10-14, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (4) summary
    cd05841
    Location:272353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563598
    zf-MYND; MYND finger
  13. NM_001370103.2NP_001357032.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variants 4 and 17-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:218299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509544
    zf-MYND; MYND finger
  14. NM_001370104.2NP_001357033.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variants 4, 16, and 18-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:218299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509544
    zf-MYND; MYND finger
  15. NM_001370105.2NP_001357034.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), as well as variants 4, 16, 17, and 19-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Related
    ENSP00000371017.5, ENST00000381604.8
    Conserved Domains (3) summary
    cd05841
    Location:218299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509544
    zf-MYND; MYND finger
  16. NM_001370106.2NP_001357035.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variants 4, 16-18, and 20-22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:218299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509544
    zf-MYND; MYND finger
  17. NM_001370107.2NP_001357036.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variants 4, 16-19, 21, and 22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:218299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509544
    zf-MYND; MYND finger
  18. NM_001370108.2NP_001357037.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variants 4, 16-20, and 22, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:218299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509544
    zf-MYND; MYND finger
  19. NM_001370109.2NP_001357038.1  zinc finger MYND domain-containing protein 11 isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variants 4 and 16-21, encodes isoform c.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:218299
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104204
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:509544
    zf-MYND; MYND finger
  20. NM_001370110.2NP_001357039.1  zinc finger MYND domain-containing protein 11 isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23), as well as variant 5, encodes isoform d.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Related
    ENSP00000473321.1, ENST00000602682.5
    Conserved Domains (3) summary
    cd05841
    Location:187268
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:478513
    zf-MYND; MYND finger
    cl02556
    Location:95173
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  21. NM_001370111.2NP_001357040.1  zinc finger MYND domain-containing protein 11 isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24), as well as variant 6, encodes isoform e.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:217298
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:104203
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:508543
    zf-MYND; MYND finger
  22. NM_001370112.2NP_001357041.1  zinc finger MYND domain-containing protein 11 isoform h

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variant 9, encodes isoform h.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (4) summary
    cd05841
    Location:255336
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:141241
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:85128
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:546581
    zf-MYND; MYND finger
  23. NM_001370113.2NP_001357042.1  zinc finger MYND domain-containing protein 11 isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variant 27, encodes isoform i.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:241322
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:532567
    zf-MYND; MYND finger
    cl02556
    Location:113227
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  24. NM_001370114.2NP_001357043.1  zinc finger MYND domain-containing protein 11 isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (27), as well as variant 6, encodes isoform i.
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Related
    ENSP00000386010.1, ENST00000402736.5
    Conserved Domains (3) summary
    cd05841
    Location:241322
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:532567
    zf-MYND; MYND finger
    cl02556
    Location:113227
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  25. NM_001370115.2NP_001357044.1  zinc finger MYND domain-containing protein 11 isoform j

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (4) summary
    cd05841
    Location:271352
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158257
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:562597
    zf-MYND; MYND finger
  26. NM_001370116.2NP_001357045.1  zinc finger MYND domain-containing protein 11 isoform k

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    Conserved Domains (4) summary
    cd05841
    Location:250331
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:136236
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:80123
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:541576
    zf-MYND; MYND finger
  27. NM_001370117.2NP_001357046.1  zinc finger MYND domain-containing protein 11 isoform l

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (4) summary
    cd05841
    Location:272353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:540575
    zf-MYND; MYND finger
  28. NM_001370118.2NP_001357047.1  zinc finger MYND domain-containing protein 11 isoform m

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    Conserved Domains (4) summary
    cd05841
    Location:232313
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:118218
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:62105
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:523558
    zf-MYND; MYND finger
  29. NM_001370119.2NP_001357048.1  zinc finger MYND domain-containing protein 11 isoform n

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (4) summary
    cd05841
    Location:252327
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158252
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:514549
    zf-MYND; MYND finger
  30. NM_001370120.2NP_001357049.1  zinc finger MYND domain-containing protein 11 isoform o

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    Conserved Domains (3) summary
    cd05841
    Location:196277
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:82182
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:487522
    zf-MYND; MYND finger
  31. NM_001370121.2NP_001357050.1  zinc finger MYND domain-containing protein 11 isoform p

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    Conserved Domains (3) summary
    cd05841
    Location:178259
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:64164
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:469504
    zf-MYND; MYND finger
  32. NM_001370122.2NP_001357051.1  zinc finger MYND domain-containing protein 11 isoform q

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:170251
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:461496
    zf-MYND; MYND finger
    cl02556
    Location:104149
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  33. NM_001370123.2NP_001357052.1  zinc finger MYND domain-containing protein 11 isoform r

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Conserved Domains (3) summary
    cd05841
    Location:153234
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    pfam01753
    Location:444479
    zf-MYND; MYND finger
    cl02556
    Location:87132
    Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  34. NM_001370124.3NP_001357053.1  zinc finger MYND domain-containing protein 11 isoform s

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922
    Conserved Domains (3) summary
    cd05841
    Location:115196
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:1101
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    pfam01753
    Location:406441
    zf-MYND; MYND finger
  35. NM_006624.7NP_006615.2  zinc finger MYND domain-containing protein 11 isoform a

    See identical proteins and their annotated locations for NP_006615.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1), as well as variants 10-15, encodes the longest isoform (a).
    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539
    Consensus CDS
    CCDS7052.2
    UniProtKB/Swiss-Prot
    Q15326
    UniProtKB/TrEMBL
    Q5BJG6, Q5UGI2
    Related
    ENSP00000381053.3, ENST00000397962.8
    Conserved Domains (4) summary
    cd05841
    Location:272353
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158258
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69
    pfam01753
    Location:563598
    zf-MYND; MYND finger
  36. NM_212479.4NP_997644.2  zinc finger MYND domain-containing protein 11 isoform b

    See identical proteins and their annotated locations for NP_997644.2

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL713922, AL731539
    Consensus CDS
    CCDS7053.2
    UniProtKB/Swiss-Prot
    Q15326
    Related
    ENSP00000424205.2, ENST00000509513.6
    Conserved Domains (3) summary
    cd05841
    Location:271352
    BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
    cd05492
    Location:158257
    Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
    cd15537
    Location:102145
    PHD_BS69; PHD finger found in protein BS69

RNA

  1. NR_163254.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL589988, AL603831, AL713922, AL731539

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    130088..254637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017015594.1XP_016871083.1  zinc finger MYND domain-containing protein 11 isoform X4

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