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PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 [ Miniopterus natalensis ]

Gene ID: 107529317, updated on 30-Mar-2024

Summary

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Gene symbol
PIK3R1
Gene description
phosphoinositide-3-kinase regulatory subunit 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Miniopterus natalensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Miniopteridae; Miniopterus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current Mnat.v1 (GCF_001595765.1) Unplaced Scaffold NW_015504327.1 (1874455..1948457)

NW_015504327.1Genomic Context describing neighboring genes Neighboring gene CD180 molecule Neighboring gene 60S ribosomal protein L21 pseudogene Neighboring gene transmembrane epididymal protein 1A-like Neighboring gene cytochrome c oxidase subunit 6B1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015504327.1 Unplaced Scaffold Reference Mnat.v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase regulatory subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Miniopterus natalensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnat.v1

Genomic

  1. NW_015504327.1 Reference Mnat.v1

    Range
    1874455..1948457
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016202675.1 → XP_016058161.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1

    Conserved Domains (6) summary
    cd09930
    Location:617 → 720
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:325 → 435
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd11910
    Location:5 → 79
    SH3_PI3K_p85alpha; Src Homology 3 domain of the p85alpha regulatory subunit of Class IA Phosphatidylinositol 3-kinases
    cd12924
    Location:440 → 600
    iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
    cd04388
    Location:114 → 302
    RhoGAP_p85; RhoGAP_p85: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in the p85 isoforms of the regulatory subunit of the class IA PI3K (phosphatidylinositol 3'-kinase). This domain is also called Bcr (breakpoint cluster region ...
    pfam16454
    Location:439 → 598
    PI3K_P85_iSH2; Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

  2. XM_016202677.1 → XP_016058163.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3

    Conserved Domains (4) summary
    cd09930
    Location:317 → 420
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:25 → 135
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12924
    Location:140 → 300
    iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
    pfam16454
    Location:139 → 298
    PI3K_P85_iSH2; Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

  3. XM_016202676.1 → XP_016058162.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2

    Conserved Domains (4) summary
    cd09930
    Location:347 → 450
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:55 → 165
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12924
    Location:170 → 330
    iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
    pfam16454
    Location:169 → 328
    PI3K_P85_iSH2; Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
Nucleotide Protein
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