Magee1 MAGE family member E1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Magee1provided by MGI
Official Full Name: MAGE family member E1provided by MGI
Primary source: MGI:MGI:2148149
See related: Ensembl:ENSMUSG00000031227 AllianceGenome:MGI:2148149
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: DAMAGE; mMage-e1
Summary: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Located in several cellular components, including dendrite; perinuclear region of cytoplasm; and postsynaptic membrane. Is expressed in several structures, including brain; egg cylinder; heart; liver; and reproductive system. Orthologous to human MAGEE1 (MAGE family member E1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human all
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Genomic context

Location:: X D; X 46.84 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (104163984..104167567)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (105120378..105123961)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

a new dystrobrevin-associated protein that may play a signaling role in brain, muscle, and peripheral nerve [DAMAGE]
Title: DAMAGE, a novel alpha-dystrobrevin-associated MAGE protein in dystrophin complexes.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in dendrite	IDA Inferred from Direct Assay more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in perinuclear region of cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in postsynaptic membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: melanoma-associated antigen E1

Names: MAGE-E1 antigen; alpha-dystrobrevin-associated MAGE Protein; melanoma antigen, family E, 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.