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LOC107457585 meiotic recombination hotspot J [ Homo sapiens (human) ]

Gene ID: 107457585, updated on 17-Jun-2019


Gene symbol
Gene description
meiotic recombination hotspot J
Gene type
biological region
Feature type(s)
misc_recomb: meiotic
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
This region is located within an intron of the dynein axonemal heavy chain 5 (DNAH5) gene, and has been identified as a meiotic recombination hotspot by sperm typing assays, molecular assays in male germ cells to identify meiotic double strand breaks, and linkage disequilibrium studies. Two distinct meiotic recombination hotspots were observed in this region by sperm typing, and are designated as the J1 hotspot and J2 hotspot sub-regions. Meiotic hotspot activity can vary widely amongst individuals and can be influenced by both the nucleotide sequence at the meiotic recombination hotspot and the specific alleles present at the PR domain 9 (PRDM9) locus. [provided by RefSeq, Mar 2016]

Genomic context

See LOC107457585 in Genome Data Viewer
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (13737335..13741925)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374660 Neighboring gene neudesin neurotrophic factor pseudogene 3 Neighboring gene ribosomal protein L29 pseudogene 13 Neighboring gene dynein axonemal heavy chain 5 Neighboring gene trio Rho guanine nucleotide exchange factor Neighboring gene small nucleolar RNA, C/D box 170 Neighboring gene OTU deubiquitinase with linear linkage specificity like

Genomic regions, transcripts, and products


Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


  1. NG_046833.1 

    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly


  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    GenBank, FASTA, Sequence Viewer (Graphics)
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