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UGT2B11 UDP glucuronosyltransferase family 2 member B11 [ Homo sapiens (human) ]

Gene ID: 10720, updated on 11-Sep-2019

Summary

Official Symbol
UGT2B11provided by HGNC
Official Full Name
UDP glucuronosyltransferase family 2 member B11provided by HGNC
Primary source
HGNC:HGNC:12545
See related
Ensembl:ENSG00000213759 MIM:603064
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Biased expression in liver (RPKM 8.5), gall bladder (RPKM 8.1) and 2 other tissues See more

Genomic context

See UGT2B11 in Genome Data Viewer
Location:
4q13.2
Exon count:
8
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (69199951..69224980, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (70066035..70080449, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene UDP-glucuronosyltransferase 2A1-like Neighboring gene uncharacterized LOC105377267 Neighboring gene UDP glucuronosyltransferase family 2 member A3 pseudogene Neighboring gene UDP glucuronosyltransferase family 2 member B4 pseudogene Neighboring gene UDP glucuronosyltransferase family 2 member A3 pseudogene Neighboring gene UDP glucuronosyltransferase family 2 member B28

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC129611, MGC129612

Gene Ontology Provided by GOA

Function Evidence Code Pubs
UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glucuronosyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
estrogen metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
xenobiotic glucuronidation IDA
Inferred from Direct Assay
more info
PubMed 
xenobiotic metabolic process TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
UDP-glucuronosyltransferase 2B11
Names
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glycosyltransferase 2 family protein
UDP glycosyltransferase 2 family, polypeptide B11
UDPGT 2B11
NP_001064.1
XP_011529852.1
XP_016863149.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001073.3NP_001064.1  UDP-glucuronosyltransferase 2B11 precursor

    See identical proteins and their annotated locations for NP_001064.1

    Status: VALIDATED

    Source sequence(s)
    AC111000, AC114797, AF016492, BG184936
    Consensus CDS
    CCDS3527.1
    UniProtKB/Swiss-Prot
    O75310
    Related
    ENSP00000387683.1, ENST00000446444.1
    Conserved Domains (1) summary
    pfam00201
    Location:24525
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    69199951..69224980 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017007660.2XP_016863149.1  UDP-glucuronosyltransferase 2B11 isoform X2

  2. XM_011531550.2XP_011529852.1  UDP-glucuronosyltransferase 2B11 isoform X1

    Conserved Domains (2) summary
    PHA03392
    Location:185423
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:24441
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
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