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Rrp12 ribosomal RNA processing 12 homolog [ Mus musculus (house mouse) ]

Gene ID: 107094, updated on 5-Mar-2024

Summary

Official Symbol
Rrp12provided by MGI
Official Full Name
ribosomal RNA processing 12 homologprovided by MGI
Primary source
MGI:MGI:2147437
See related
Ensembl:ENSMUSG00000035049 AllianceGenome:MGI:2147437
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0690
Summary
Predicted to be involved in rRNA processing. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and plasma membrane. Predicted to be active in nucleolus. Orthologous to human RRP12 (ribosomal RNA processing 12 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 14.1), CNS E11.5 (RPKM 6.9) and 28 other tissues See more
Orthologs
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Genomic context

See Rrp12 in Genome Data Viewer
Location:
19 C3; 19 35.36 cM
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (41847922..41884592, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (41859483..41896153, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_46163 Neighboring gene frequently rearranged in advanced T cell lymphomas Neighboring gene STARR-positive B cell enhancer mm9_chr19:41922780-41923081 Neighboring gene frequently rearranged in advanced T cell lymphomas 2 Neighboring gene STARR-positive B cell enhancer ABC_E4281 Neighboring gene predicted gene, 46644 Neighboring gene STARR-positive B cell enhancer ABC_E7659 Neighboring gene phosphoglycerate mutase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199447.2NP_955518.1  RRP12-like protein

    See identical proteins and their annotated locations for NP_955518.1

    Status: PROVISIONAL

    Source sequence(s)
    BC062977
    Consensus CDS
    CCDS29814.1
    UniProtKB/Swiss-Prot
    Q6P5B0, Q7TMI5, Q80TU2
    UniProtKB/TrEMBL
    Q3UJA1
    Related
    ENSMUSP00000039853.4, ENSMUST00000038677.5
    Conserved Domains (2) summary
    pfam08161
    Location:473670
    NUC173; NUC173 domain
    pfam14632
    Location:11571204
    SPT6_acidic; Acidic N-terminal SPT6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    41847922..41884592 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030250683.1XP_030106543.1  RRP12-like protein isoform X1

    Conserved Domains (1) summary
    pfam08161
    Location:2192
    NUC173; NUC173 domain