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SUOX sulfite oxidase [ Gallus gallus (chicken) ]

Gene ID: 107055404, updated on 5-Aug-2026
Symbol
SUOXprovided by CGNC
Full Name
sulfite oxidaseprovided by CGNC
Primary source
CGNC:49732
See related
Ensembl:ENSGALG00010024789
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
all
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Try the new Transcripts and proteins table
See SUOX in Genome Data Viewer
Location:
chromosome: 34
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 34 NC_052565.1 (1352722..1356284)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 34 NC_052606.1 (1300174..1303727, complement)

Chromosome 34 - NC_052565.1Genomic Context describing neighboring genes Neighboring gene premelanosome protein Neighboring gene cyclin dependent kinase 2 Neighboring gene RAB5B, member RAS oncogene family Neighboring gene IKAROS family zinc finger 4 Neighboring gene uncharacterized LOC112530903 Neighboring gene ribosomal protein S26

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A quantum-mechanical study of the reaction mechanism of sulfite oxidase. van Severen MC, et al. J Biol Inorg Chem, 2014 Oct. PMID 24957901
  2. The structures of the C185S and C185A mutants of sulfite oxidase reveal rearrangement of the active site. Qiu JA, et al. Biochemistry, 2010 May 11. PMID 20356030
  3. Exchangeable oxygens in the vicinity of the molybdenum center of the high-pH form of sulfite oxidase and sulfite dehydrogenase. Astashkin AV, et al. Phys Chem Chem Phys, 2009 Aug 21. PMID 19639147, Free PMC Article
  4. Amino acid sequence of the 'b5-like' heme-binding domain from chicken sulfite oxidase. Guiard B, et al. Eur J Biochem, 1979 Oct 15. PMID 510290
  5. Effects of interdomain tether length and flexibility on the kinetics of intramolecular electron transfer in human sulfite oxidase. Johnson-Winters K, et al. Biochemistry, 2010 Feb 16. PMID 20063894, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Double-mutant sulfite oxidase variants demonstrate a marked decrease in sulfite oxidase activity but gain nitrate reductase activity.
    Title: Structure-based alteration of substrate specificity and catalytic activity of sulfite oxidase from sulfite oxidation to nitrate reduction.
  2. The intramolecular electron transfer rate constant of chicken sulfite oxidase is twice that of human and could be due to the greater flexibility of the polypeptide tether in the chicken enzyme, with four alanine residues compared to one for human.
    Title: Effects of interdomain tether length and flexibility on the kinetics of intramolecular electron transfer in human sulfite oxidase.
  3. The oxidation of sulfite to sulfate by two different models of the active site of sulfite oxidase has been studied. Both protonated and deprotonated substrates were tested.
    Title: A quantum-mechanical study of the reaction mechanism of sulfite oxidase.
  4. The active sites of the C185S and C185A sulfite oxidase mutants are catalytically inactive.
    Title: The structures of the C185S and C185A mutants of sulfite oxidase reveal rearrangement of the active site.
  5. The active center of sulfite oxidase contains three types of exchangeable oxygen atoms at the molybdenum center.
    Title: Exchangeable oxygens in the vicinity of the molybdenum center of the high-pH form of sulfite oxidase and sulfite dehydrogenase.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables molybdenum ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables molybdopterin cofactor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
sulfite oxidase
Names
nitrite reductase, mitochondrial
NP_001383605.1

Length

  • 640
XP_015155798.1
XP_040549966.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396676.1 → NP_001383605.1  sulfite oxidase

    Status: VALIDATED

    Source sequence(s)
    CN228195, JAENSK010000490
    UniProtKB/TrEMBL
    A0A8V1A250
    Related
    ENSGALP00010037268.1, ENSGALT00010060509.1
    Conserved Domains (2) summary
    PLN02252
    Location:181 → 288
    PLN02252; nitrate reductase [NADPH]
    cd02111
    Location:280 → 638
    eukary_SO_Moco; molybdopterin binding domain of sulfite oxidase (SO). SO catalyzes the terminal reaction in the oxidative degradation of the sulfur-containing amino acids cysteine and methionine. Common features of all known members of the sulfite oxidase (SO) family of ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052565.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1352722..1356284
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015300312.4 → XP_015155798.1  sulfite oxidase isoform X1

    UniProtKB/Swiss-Prot
    P07850
    UniProtKB/TrEMBL
    A0A8V0ZUQ1
    Related
    ENSGALP00010037274.1, ENSGALT00010060515.1
    Conserved Domains (2) summary
    cd02111
    Location:130 → 488
    eukary_SO_Moco; molybdopterin binding domain of sulfite oxidase (SO). SO catalyzes the terminal reaction in the oxidative degradation of the sulfur-containing amino acids cysteine and methionine. Common features of all known members of the sulfite oxidase (SO) family of ...
    pfam00173
    Location:32 → 106
    Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052606.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    1300174..1303727 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040694032.2 → XP_040549966.1  sulfite oxidase isoform X1

    UniProtKB/Swiss-Prot
    P07850
    UniProtKB/TrEMBL
    A0A8V0ZUQ1
    Conserved Domains (2) summary
    cd02111
    Location:130 → 488
    eukary_SO_Moco; molybdopterin binding domain of sulfite oxidase (SO). SO catalyzes the terminal reaction in the oxidative degradation of the sulfur-containing amino acids cysteine and methionine. Common features of all known members of the sulfite oxidase (SO) family of ...
    pfam00173
    Location:32 → 106
    Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P07850.3 GenPept UniProtKB/Swiss-Prot:P07850

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.