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Hmgxb3 HMG box domain containing 3 [ Mus musculus (house mouse) ]

Gene ID: 106894, updated on 9-May-2024

Summary

Official Symbol
Hmgxb3provided by MGI
Official Full Name
HMG box domain containing 3provided by MGI
Primary source
MGI:MGI:2441817
See related
Ensembl:ENSMUSG00000024622 AllianceGenome:MGI:2441817
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0194; 2510002C16Rik; A630042L21Rik
Summary
Is expressed in brain; early conceptus; and genitourinary system. Orthologous to human HMGXB3 (HMG-box containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 11.8), adrenal adult (RPKM 11.0) and 28 other tissues See more
Orthologs
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Genomic context

See Hmgxb3 in Genome Data Viewer
Location:
18 E1; 18 34.41 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (61264349..61310122, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (61131277..61177050, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene platelet derived growth factor receptor, beta polypeptide Neighboring gene Csf1r promoter/intronic regulatory region Neighboring gene colony stimulating factor 1 receptor Neighboring gene microRNA 6983 Neighboring gene predicted gene, 26403 Neighboring gene predicted gene, 50614 Neighboring gene STARR-positive B cell enhancer ABC_E7591 Neighboring gene solute carrier family 26 (sulfate transporter), member 2 Neighboring gene STARR-seq mESC enhancer starr_44740 Neighboring gene predicted gene, 52353 Neighboring gene phosphodiesterase 6A, cGMP-specific, rod, alpha Neighboring gene ribosomal protein S2, pseudogene 10

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
HMG domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134134.2NP_598895.2  HMG domain-containing protein 3 isoform 2

    See identical proteins and their annotated locations for NP_598895.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame segment in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    AB045322, AK041866, AK132529, BC025148, BG061435, BU611563
    Consensus CDS
    CCDS50301.1
    UniProtKB/TrEMBL
    G3X9M3, Q6PEF4
    Related
    ENSMUSP00000089498.5, ENSMUST00000091884.6
    Conserved Domains (1) summary
    smart00398
    Location:4099
    HMG; high mobility group
  2. NM_178277.1NP_840061.1  HMG domain-containing protein 3 isoform 1

    See identical proteins and their annotated locations for NP_840061.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. It encodes the longer protein (isoform 1).
    Source sequence(s)
    AB045322, BC025148, BC058089
    Consensus CDS
    CCDS89249.1
    UniProtKB/TrEMBL
    Q6AXF8, Q6PEF4
    Related
    ENSMUSP00000158376.2, ENSMUST00000235480.2
    Conserved Domains (1) summary
    smart00398
    Location:4099
    HMG; high mobility group

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    61264349..61310122 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017317779.1XP_017173268.1  HMG domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    Q6NZP6, Q9JJ64
    Conserved Domains (1) summary
    pfam18717
    Location:318392
    CxC4; CxC4 like cysteine cluster associated with KDZ transposases