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Smim3 small integral membrane protein 3 [ Mus musculus (house mouse) ]

Gene ID: 106878, updated on 12-May-2024

Summary

Official Symbol
Smim3provided by MGI
Official Full Name
small integral membrane protein 3provided by MGI
Primary source
MGI:MGI:1917088
See related
Ensembl:ENSMUSG00000038059 AllianceGenome:MGI:1917088
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Nid67; cI-41; 2010002N04Rik
Summary
Predicted to enable identical protein binding activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in liver left lobe; liver right lobe; and thyroid gland. Orthologous to human SMIM3 (small integral membrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 8.4), lung adult (RPKM 8.1) and 26 other tissues See more
Orthologs
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Genomic context

Location:
18 D3; 18 34.36 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (60607263..60635055, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (60474191..60518949, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted pseudogene 6960 Neighboring gene interferon-inducible GTPase-like pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr18:60622203-60622504 Neighboring gene STARR-seq mESC enhancer starr_44715 Neighboring gene predicted gene, 46628 Neighboring gene dynactin 4 Neighboring gene predicted gene, 52358

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (1) 
  • Targeted (1)  1 citation

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
small integral membrane protein 3
Names
NGF-induced differentiation clone 67 protein
putative small membrane protein NID67
small membrane protein NID67

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134133.2NP_598894.1  small integral membrane protein 3

    See identical proteins and their annotated locations for NP_598894.1

    Status: VALIDATED

    Source sequence(s)
    AF313412, AK143383, AK155873
    Consensus CDS
    CCDS37831.1
    UniProtKB/Swiss-Prot
    Q921E9, Q99PE5
    UniProtKB/TrEMBL
    Q3TAJ2, Q3U1M0
    Related
    ENSMUSP00000039285.7, ENSMUST00000042710.8
    Conserved Domains (1) summary
    pfam17307
    Location:160
    Smim3; Small integral membrane protein 3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    60607263..60635055 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011246797.3XP_011245099.1  small integral membrane protein 3 isoform X2

    See identical proteins and their annotated locations for XP_011245099.1

    UniProtKB/Swiss-Prot
    Q921E9, Q99PE5
    UniProtKB/TrEMBL
    Q3TAJ2, Q3U1M0
    Conserved Domains (1) summary
    pfam17307
    Location:160
    Smim3; Small integral membrane protein 3
  2. XM_006525481.5XP_006525544.2  small integral membrane protein 3 isoform X1