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Tcf19 transcription factor 19 [ Mus musculus (house mouse) ]

Gene ID: 106795, updated on 26-Sep-2022

Summary

Official Symbol
Tcf19provided by MGI
Official Full Name
transcription factor 19provided by MGI
Primary source
MGI:MGI:103180
See related
Ensembl:ENSMUSG00000050410 AllianceGenome:MGI:103180
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5730403J10Rik
Summary
Acts upstream of or within G1/S transition of mitotic cell cycle; regulation of gene expression; and type B pancreatic cell proliferation. Located in nucleus. Is expressed in forebrain; genitourinary system; and limb. Orthologous to human TCF19 (transcription factor 19). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in limb E14.5 (RPKM 21.9), thymus adult (RPKM 20.3) and 25 other tissues See more
Orthologs
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Genomic context

See Tcf19 in Genome Data Viewer
Location:
17; 17 B1
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (35823627..35827730, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35512730..35516837, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene Pou5f1 5' regulatory region Neighboring gene predicted gene, 32362 Neighboring gene POU domain, class 5, transcription factor 1 Neighboring gene coiled-coil alpha-helical rod protein 1 Neighboring gene psoriasis susceptibility 1 candidate 2 (human)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transcription factor 19-like protein
Names
SC1 protein homolog
TCF-19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163763.1NP_001157235.1  transcription factor 19-like protein

    See identical proteins and their annotated locations for NP_001157235.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
    Source sequence(s)
    AK004231, AK077414, AK078697, BB873636, BG082313
    Consensus CDS
    CCDS50089.1
    UniProtKB/Swiss-Prot
    Q99KJ5
    UniProtKB/TrEMBL
    G3XA31
    Related
    ENSMUSP00000125167.2, ENSMUST00000160885.2
    Conserved Domains (2) summary
    cd00060
    Location:5123
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR03354
    Location:36240
    VI_FHA; type VI secretion system FHA domain protein
  2. NM_001163764.1NP_001157236.1  transcription factor 19-like protein

    See identical proteins and their annotated locations for NP_001157236.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AK004231, AK077414, BB873636, BG082313, CX220762
    Consensus CDS
    CCDS50089.1
    UniProtKB/Swiss-Prot
    Q99KJ5
    UniProtKB/TrEMBL
    G3XA31
    Conserved Domains (2) summary
    cd00060
    Location:5123
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR03354
    Location:36240
    VI_FHA; type VI secretion system FHA domain protein
  3. NM_025674.2NP_079950.2  transcription factor 19-like protein

    See identical proteins and their annotated locations for NP_079950.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three variants encode the same protein.
    Source sequence(s)
    AK004231, AK077414, BB873636, BG082313
    Consensus CDS
    CCDS50089.1
    UniProtKB/Swiss-Prot
    Q99KJ5
    UniProtKB/TrEMBL
    G3XA31
    Related
    ENSMUSP00000125310.2, ENSMUST00000161012.8
    Conserved Domains (2) summary
    cd00060
    Location:5123
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR03354
    Location:36240
    VI_FHA; type VI secretion system FHA domain protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    35823627..35827730 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249438.2XP_030105298.1  transcription factor 19-like protein isoform X1

    UniProtKB/TrEMBL
    G3XA31
    Conserved Domains (2) summary
    cd00060
    Location:5123
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    TIGR03354
    Location:36240
    VI_FHA; type VI secretion system FHA domain protein