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Wdr90 WD repeat domain 90 [ Mus musculus (house mouse) ]

Gene ID: 106618, updated on 5-Mar-2024

Summary

Official Symbol
Wdr90provided by MGI
Official Full Name
WD repeat domain 90provided by MGI
Primary source
MGI:MGI:1921267
See related
Ensembl:ENSMUSG00000073434 AllianceGenome:MGI:1921267
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA1924; 3230401M21Rik
Summary
Predicted to be involved in cilium assembly. Predicted to act upstream of or within cell projection organization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in centriole. Is expressed in choroid invagination; diencephalon roof plate; metencephalon part of 4th ventricle choroid plexus; and olfactory epithelium. Orthologous to human WDR90 (WD repeat domain 90). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 17.6), thymus adult (RPKM 16.0) and 28 other tissues See more
Orthologs
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Genomic context

See Wdr90 in Genome Data Viewer
Location:
17 A3.3; 17 12.94 cM
Exon count:
41
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (26063708..26080489, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25844734..25861515, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene rhomboid like 1 Neighboring gene ras homolog family member T2 Neighboring gene MAPK regulated corepressor interacting protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E10938 Neighboring gene nuclear encoded tRNA glycine 7 (anticodon CCC)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cell projection organization IEA
Inferred from Electronic Annotation
more info
 
involved_in cilium assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in centriole IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in centriole ISO
Inferred from Sequence Orthology
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
WD repeat-containing protein 90

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163766.1NP_001157238.1  WD repeat-containing protein 90

    Status: VALIDATED

    Source sequence(s)
    AK129465, BB573604, BB765139, BY232715, CJ102018, CN526398
    Consensus CDS
    CCDS50037.1
    UniProtKB/Swiss-Prot
    Q6ZPG2, Q80VI2, Q8BI97, Q8R3G7, Q921X4
    UniProtKB/TrEMBL
    H7BX49
    Related
    ENSMUSP00000078426.9, ENSMUST00000079461.15
    Conserved Domains (4) summary
    COG2319
    Location:12751698
    WD40; WD40 repeat [General function prediction only]
    pfam05018
    Location:63257
    DUF667; Protein of unknown function (DUF667)
    sd00039
    Location:13041346
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:7771077
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    26063708..26080489 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_134124.1: Suppressed sequence

    Description
    NM_134124.1: This RefSeq was suppressed temporarily based on the calculation that the annotated protein was shorter than a protein or proteins from a putative ortholog.