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RASL10A RAS like family 10 member A [ Homo sapiens (human) ]

Gene ID: 10633, updated on 11-Jun-2021

Summary

Official Symbol
RASL10Aprovided by HGNC
Official Full Name
RAS like family 10 member Aprovided by HGNC
Primary source
HGNC:HGNC:16954
See related
Ensembl:ENSG00000100276 MIM:602220
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RRP22
Expression
Biased expression in brain (RPKM 6.1) and testis (RPKM 0.5) See more
Orthologs
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Genomic context

See RASL10A in Genome Data Viewer
Location:
22q12.2
Exon count:
6
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 22 NC_000022.11 (29312933..29319618, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (29708922..29711686, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene EWS RNA binding protein 1 Neighboring gene growth arrest specific 2 like 1 Neighboring gene small nucleolar RNA, C/D box 125 Neighboring gene adaptor related protein complex 1 subunit beta 1 Neighboring gene ret finger protein like 1 Neighboring gene uncharacterized LOC102723305

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • AC002059.10

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein activity IEA
Inferred from Electronic Annotation
more info
 
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in small GTPase mediated signal transduction TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ras-like protein family member 10A
Names
ras-like protein RRP22
ras-related protein on chromosome 22
NP_006468.1
XP_011528123.1
XP_011528124.1
XP_011528125.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006477.5NP_006468.1  ras-like protein family member 10A

    See identical proteins and their annotated locations for NP_006468.1

    Status: VALIDATED

    Source sequence(s)
    AC002059, BX111994, Y07847
    Consensus CDS
    CCDS13854.1
    UniProtKB/Swiss-Prot
    Q92737
    UniProtKB/TrEMBL
    A0A024R1C8
    Related
    ENSP00000216101.6, ENST00000216101.7
    Conserved Domains (1) summary
    cl38936
    Location:5203
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p13 Primary Assembly

    Range
    29312933..29319618 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011529823.1XP_011528125.1  ras-like protein family member 10A isoform X2

    Conserved Domains (1) summary
    cl21455
    Location:25155
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  2. XM_011529821.1XP_011528123.1  ras-like protein family member 10A isoform X1

    See identical proteins and their annotated locations for XP_011528123.1

    Conserved Domains (1) summary
    cl21455
    Location:86223
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
  3. XM_011529822.1XP_011528124.1  ras-like protein family member 10A isoform X1

    See identical proteins and their annotated locations for XP_011528124.1

    Conserved Domains (1) summary
    cl21455
    Location:86223
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001007279.1: Suppressed sequence

    Description
    NM_001007279.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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