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Mfsd5 major facilitator superfamily domain containing 5 [ Mus musculus (house mouse) ]

Gene ID: 106073, updated on 11-Apr-2024

Summary

Official Symbol
Mfsd5provided by MGI
Official Full Name
major facilitator superfamily domain containing 5provided by MGI
Primary source
MGI:MGI:2145901
See related
Ensembl:ENSMUSG00000045665 AllianceGenome:MGI:2145901
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AW556797; D15Mgi27
Summary
Predicted to enable molybdate ion transmembrane transporter activity. Predicted to be involved in molybdate ion transport. Predicted to act upstream of or within ion transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system; liver; and spinal cord. Orthologous to human MFSD5 (major facilitator superfamily domain containing 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 50.9), mammary gland adult (RPKM 49.0) and 28 other tissues See more
Orthologs
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Genomic context

See Mfsd5 in Genome Data Viewer
Location:
15 F2; 15 57.44 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (102187891..102190179)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (102279456..102281744)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39826 Neighboring gene STARR-seq mESC enhancer starr_39827 Neighboring gene retinoic acid receptor, gamma Neighboring gene STARR-seq mESC enhancer starr_39828 Neighboring gene predicted gene 9918 Neighboring gene STARR-seq mESC enhancer starr_39829 Neighboring gene STARR-positive B cell enhancer ABC_E5520 Neighboring gene extra spindle pole bodies 1, separase Neighboring gene STARR-positive B cell enhancer ABC_E7421 Neighboring gene microRNA 12187 Neighboring gene prefoldin 5

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables molybdate ion transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in molybdate ion transport ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
molybdate-anion transporter
Names
major facilitator superfamily domain-containing protein 5
molybdate transporter 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134100.4NP_598861.1  molybdate-anion transporter

    See identical proteins and their annotated locations for NP_598861.1

    Status: PROVISIONAL

    Source sequence(s)
    AK089268
    Consensus CDS
    CCDS27877.1
    UniProtKB/Swiss-Prot
    Q921Y4
    Related
    ENSMUSP00000061997.5, ENSMUST00000051341.6
    Conserved Domains (1) summary
    cl21472
    Location:6328
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    102187891..102190179
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)