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iqgap1 IQ motif containing GTPase activating protein 1 [ Fundulus heteroclitus (mummichog) ]

Gene ID: 105938828, updated on 20-Aug-2024
Gene symbol
iqgap1
Gene description
IQ motif containing GTPase activating protein 1
See related
EnsemblRapid:ENSFHEG00000018186
Gene type
protein coding
RefSeq status
MODEL
Organism
Fundulus heteroclitus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Fundulidae; Fundulus
Orthologs
all
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See iqgap1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
37
Annotation release Status Assembly Chr Location
102 current MU-UCD_Fhet_4.1 (GCF_011125445.2) 4 NC_046364.1 (3946490..4019470)
101 previous assembly Fundulus_heteroclitus-3.0.2 (GCF_000826765.1) Unplaced Scaffold NW_012234521.1 (366603..433286, complement)

Chromosome 4 - NC_046364.1Genomic Context describing neighboring genes Neighboring gene cocaine- and amphetamine-regulated transcript 3 Neighboring gene cocaine- and amphetamine-regulated transcript-like Neighboring gene ras GTPase-activating-like protein IQGAP1 Neighboring gene CREB regulated transcription coactivator 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
ras GTPase-activating-like protein IQGAP1
Names
Ras GTPase-activating IQGAP1-like protein
Ras GTPase-activating IQGAP3-like protein

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RefSeqs of Annotated Genomes: Fundulus heteroclitus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MU-UCD_Fhet_4.1 Primary Assembly

Genomic

  1. NC_046364.1 Reference MU-UCD_Fhet_4.1 Primary Assembly

    Range
    3946490..4019470
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036135896.1 → XP_035991789.1  ras GTPase-activating-like protein IQGAP1

    UniProtKB/TrEMBL
    A0A3Q2QU79
    Related
    ENSFHEP00000031456.2, ENSFHET00000023923.2
    Conserved Domains (5) summary
    smart00015
    Location:775 → 793
    IQ; Calmodulin-binding motif
    COG5261
    Location:873 → 1653
    IQG1; Protein involved in regulation of cellular morphogenesis/cytokinesis [Cell division and chromosome partitioning / Signal transduction mechanisms]
    cd00201
    Location:680 → 709
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd21274
    Location:35 → 188
    CH_IQGAP1; calponin homology (CH) domain found in Ras GTPase-activating-like protein IQGAP1
    cl02569
    Location:1000 → 1379
    RasGAP; Ras GTPase Activating Domain
Nucleotide Protein
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