Envelope surface glycoprotein gp120
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env
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HIV-1 gp120 interacts with IFITM2 |
PubMed
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|
env
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HIV-1 Env processing from gp160 to gp120/41 is inhibited by IFITM2 |
PubMed
|
Envelope surface glycoprotein gp160, precursor
|
env
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HIV-1 gp160 interacts with IFITM2 |
PubMed
|
|
env
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IFITM2/3 proteins are co-localize with HIV-1 Env in the cell interior, while surface-associated IFITM2/3 proteins are present at virus budding sites containing HIV-1 Gag and Env proteins in CD4+ T cells |
PubMed
|
Envelope transmembrane glycoprotein gp41
|
env
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HIV-1 gp120 interacts with IFITM2 |
PubMed
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|
env
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HIV-1 Env processing from gp160 to gp120/41 is inhibited by IFITM2 |
PubMed
|
Nef
|
nef
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IFITM2 significantly downregulates the expression of HIV-1 Nef by interfering with Tat/TAR-mediated expression |
PubMed
|
Pr55(Gag)
|
gag
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IFITM1, IFITM2, and IFITM3 proteins (IFITMs) co-localize with HIV-1 Gag in virus-producing cells and co-assemble with Gag into budding particles |
PubMed
|
|
gag
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Endogenous IFITM1/2/3 proteins are upregulated in activated CD4+ T cells and incorporated into HIV-1 Gag/p24-associated virions during infection |
PubMed
|
|
gag
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IFITM2/3 proteins are co-localize with HIV-1 Env in the cell interior, while surface-associated IFITM2/3 proteins are present at virus budding sites containing HIV-1 Gag and Env proteins in CD4+ T cells |
PubMed
|
|
gag
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IFITM2 significantly downregulates the expression of HIV-1 Gag and CA by interfering with both Rev/RRE- and Tat/TAR-mediated expression |
PubMed
|
Vif
|
vif
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IFITM2 significantly downregulates the expression of HIV-1 Vif by interfering with both Rev/RRE- and Tat/TAR-mediated expression |
PubMed
|
Vpr
|
vpr
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HIV-1 Vpr upregulates the expression of IFITM1 in human monocyte-derived dendritic cells |
PubMed
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|
vpr
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IFITM1, 2 or 3 marginally inhibit the entry of HIV-1 NL4-3 and SIV Mac into TZM-bl by measuring the cleavage of CCF2 by BlaM-Vpr that enters the cytoplasm together with viral cores |
PubMed
|
capsid
|
gag
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IFITM1, IFITM2, and IFITM3 proteins (IFITMs) co-localize with HIV-1 CA in velocity gradients, indicating that IFITMs are virion-associated proteins |
PubMed
|
|
gag
|
Endogenous IFITM1/2/3 proteins are upregulated in activated CD4+ T cells and incorporated into HIV-1 Gag/p24-associated virions during infection |
PubMed
|
|
gag
|
IFITM2 significantly downregulates the expression of HIV-1 Gag and CA by interfering with both Rev/RRE- and Tat/TAR-mediated expression |
PubMed
|