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SORBS1 sorbin and SH3 domain containing 1 [ Homo sapiens (human) ]

Gene ID: 10580, updated on 24-Nov-2020

Summary

Official Symbol
SORBS1provided by HGNC
Official Full Name
sorbin and SH3 domain containing 1provided by HGNC
Primary source
HGNC:HGNC:14565
See related
Ensembl:ENSG00000095637 MIM:605264
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CAP; FLAF2; R85FL; SH3D5; SORB1; SH3P12
Summary
This gene encodes a CBL-associated protein which functions in the signaling and stimulation of insulin. Mutations in this gene may be associated with human disorders of insulin resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Expression
Broad expression in fat (RPKM 111.7), heart (RPKM 81.6) and 15 other tissues See more
Orthologs

Genomic context

See SORBS1 in Genome Data Viewer
Location:
10q24.1
Exon count:
39
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (95311773..95561439, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (97071530..97321171, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene PDZ and LIM domain 1 Neighboring gene CRISPRi-validated cis-regulatory element chr10.3436 Neighboring gene Sharpr-MPRA regulatory region 12220 Neighboring gene VISTA enhancer hs2353 Neighboring gene RPS3A pseudogene 36 Neighboring gene aldehyde dehydrogenase 18 family member A1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association study of suicide attempts in mood disorder patients.
GeneReviews: Not available
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
GeneReviews: Not available
Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.
GeneReviews: Not available
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
GeneReviews: Not available
SORBS1 gene, a new candidate for diabetic nephropathy: results from a multi-stage genome-wide association study in patients with type 1 diabetes.
GeneReviews: Not available

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Tat tat Microarray analysis indicates HIV-1 Tat-induced downregulation of sorbin and SH3 domain containing 1 (SORBS1) in primary human brain microvascular endothelial cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ12406, KIAA1296, DKFZp451C066, DKFZp586P1422

Gene Ontology Provided by GOA

Function Evidence Code Pubs
actin binding TAS
Traceable Author Statement
more info
PubMed 
cytoskeletal protein binding TAS
Traceable Author Statement
more info
PubMed 
insulin receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
signaling receptor complex adaptor activity IDA
Inferred from Direct Assay
more info
PubMed 
signaling receptor complex adaptor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
cell-matrix adhesion TAS
Traceable Author Statement
more info
PubMed 
cellular response to insulin stimulus ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
focal adhesion assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
insulin receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
muscle contraction TAS
Traceable Author Statement
more info
 
positive regulation of glucose import ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of glycogen biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of insulin receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of lipid biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of protein localization to plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
stress fiber assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
adherens junction ISS
Inferred from Sequence or Structural Similarity
more info
 
cell-substrate junction ISS
Inferred from Sequence or Structural Similarity
more info
 
centrosome IDA
Inferred from Direct Assay
more info
 
cytosol ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
focal adhesion IDA
Inferred from Direct Assay
more info
 
membrane raft ISS
Inferred from Sequence or Structural Similarity
more info
 
nuclear matrix IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
stress fiber ISS
Inferred from Sequence or Structural Similarity
more info
 
zonula adherens TAS
Traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
sorbin and SH3 domain-containing protein 1
Names
Fas-ligand associated factor 2
SH3 domain protein 5
c-Cbl associated protein
ponsin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_034041.1 RefSeqGene

    Range
    5001..254648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001034954.3NP_001030126.2  sorbin and SH3 domain-containing protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
    Consensus CDS
    CCDS31255.1
    Related
    ENSP00000355136.3, ENST00000361941.7
  2. NM_001034955.2NP_001030127.2  sorbin and SH3 domain-containing protein 1 isoform 4

    Status: REVIEWED

    Source sequence(s)
    AL158165
    Consensus CDS
    CCDS31254.1
    Related
    ENSP00000277982.5, ENST00000277982.9
  3. NM_001034956.2NP_001030128.2  sorbin and SH3 domain-containing protein 1 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AL158165
    Consensus CDS
    CCDS31256.1
    Related
    ENSP00000360291.2, ENST00000371245.7
  4. NM_001034957.3NP_001030129.2  sorbin and SH3 domain-containing protein 1 isoform 7

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  5. NM_001290294.2NP_001277223.2  sorbin and SH3 domain-containing protein 1 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
    Consensus CDS
    CCDS73169.1
    Related
    ENSP00000360271.3, ENST00000371227.8
  6. NM_001290295.2NP_001277224.2  sorbin and SH3 domain-containing protein 1 isoform 9

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) has multiple differences in the coding region but maintains the reading frame, compared to variant 3. The encoded protein (isoform 9) is shorter than isoform 3.
    Source sequence(s)
    AL157890, AL158165
  7. NM_001290296.2NP_001277225.2  sorbin and SH3 domain-containing protein 1 isoform 10

    Status: REVIEWED

    Source sequence(s)
    AL158165
    Consensus CDS
    CCDS76327.1
    Related
    ENSP00000277984.4, ENST00000354106.7
  8. NM_001290297.3NP_001277226.2  sorbin and SH3 domain-containing protein 1 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
    Consensus CDS
    CCDS76326.1
  9. NM_001290298.3NP_001277227.2  sorbin and SH3 domain-containing protein 1 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  10. NM_001377197.1NP_001364126.1  sorbin and SH3 domain-containing protein 1 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  11. NM_001377198.1NP_001364127.1  sorbin and SH3 domain-containing protein 1 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  12. NM_001377199.1NP_001364128.1  sorbin and SH3 domain-containing protein 1 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  13. NM_001377200.1NP_001364129.1  sorbin and SH3 domain-containing protein 1 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  14. NM_001377201.1NP_001364130.1  sorbin and SH3 domain-containing protein 1 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  15. NM_001377202.1NP_001364131.1  sorbin and SH3 domain-containing protein 1 isoform 18

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  16. NM_001377203.1NP_001364132.1  sorbin and SH3 domain-containing protein 1 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  17. NM_001377204.1NP_001364133.1  sorbin and SH3 domain-containing protein 1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  18. NM_001377205.1NP_001364134.1  sorbin and SH3 domain-containing protein 1 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  19. NM_001377206.1NP_001364135.1  sorbin and SH3 domain-containing protein 1 isoform 22

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  20. NM_001377207.1NP_001364136.1  sorbin and SH3 domain-containing protein 1 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  21. NM_001377208.1NP_001364137.1  sorbin and SH3 domain-containing protein 1 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  22. NM_001377209.1NP_001364138.1  sorbin and SH3 domain-containing protein 1 isoform 25

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  23. NM_001384447.1NP_001371376.1  sorbin and SH3 domain-containing protein 1 isoform 26

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  24. NM_001384448.1NP_001371377.1  sorbin and SH3 domain-containing protein 1 isoform 27

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  25. NM_001384449.1NP_001371378.1  sorbin and SH3 domain-containing protein 1 isoform 28

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  26. NM_001384450.1NP_001371379.1  sorbin and SH3 domain-containing protein 1 isoform 29

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  27. NM_001384451.1NP_001371380.1  sorbin and SH3 domain-containing protein 1 isoform 30

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
    Related
    ENSP00000475901.1, ENST00000607232.5
  28. NM_001384452.1NP_001371381.1  sorbin and SH3 domain-containing protein 1 isoform 31

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  29. NM_001384453.1NP_001371382.1  sorbin and SH3 domain-containing protein 1 isoform 32

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  30. NM_001384454.1NP_001371383.1  sorbin and SH3 domain-containing protein 1 isoform 32

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  31. NM_001384455.1NP_001371384.1  sorbin and SH3 domain-containing protein 1 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
    Related
    ENSP00000360283.1, ENST00000371239.5
  32. NM_001384456.1NP_001371385.1  sorbin and SH3 domain-containing protein 1 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  33. NM_001384457.1NP_001371386.1  sorbin and SH3 domain-containing protein 1 isoform 11

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  34. NM_001384458.1NP_001371387.1  sorbin and SH3 domain-containing protein 1 isoform 33

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  35. NM_001384459.1NP_001371388.1  sorbin and SH3 domain-containing protein 1 isoform 34

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  36. NM_001384460.1NP_001371389.1  sorbin and SH3 domain-containing protein 1 isoform 35

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  37. NM_001384461.1NP_001371390.1  sorbin and SH3 domain-containing protein 1 isoform 36

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  38. NM_001384462.1NP_001371391.1  sorbin and SH3 domain-containing protein 1 isoform 37

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  39. NM_001384463.1NP_001371392.1  sorbin and SH3 domain-containing protein 1 isoform 38

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  40. NM_001384464.1NP_001371393.1  sorbin and SH3 domain-containing protein 1 isoform 39

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  41. NM_001384465.1NP_001371394.1  sorbin and SH3 domain-containing protein 1 isoform 20

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
  42. NM_006434.4NP_006425.3  sorbin and SH3 domain-containing protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
    Consensus CDS
    CCDS31252.1
    Related
    ENSP00000360285.1, ENST00000371241.5
  43. NM_015385.4NP_056200.2  sorbin and SH3 domain-containing protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
    Consensus CDS
    CCDS7442.1
    Related
    ENSP00000360295.2, ENST00000371249.6
    Conserved Domains (4) summary
    smart00459
    Location:335380
    Sorb; Sorbin homologous domain
    cd11916
    Location:757815
    SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11919
    Location:578632
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:652709
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
  44. NM_024991.3NP_079267.2  sorbin and SH3 domain-containing protein 1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AL157890, AL158165
    Consensus CDS
    CCDS31253.1
    Related
    ENSP00000302556.6, ENST00000306402.10
    Conserved Domains (5) summary
    smart00459
    Location:244289
    Sorb; Sorbin homologous domain
    cd11916
    Location:722780
    SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11919
    Location:543597
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:617674
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    pfam15449
    Location:83241
    Retinal; Retinal protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    95311773..95561439 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017015508.2XP_016870997.1  sorbin and SH3 domain-containing protein 1 isoform X15

  2. XM_017015506.2XP_016870995.1  sorbin and SH3 domain-containing protein 1 isoform X12

  3. XM_017015511.2XP_016871000.1  sorbin and SH3 domain-containing protein 1 isoform X18

  4. XM_017015504.2XP_016870993.1  sorbin and SH3 domain-containing protein 1 isoform X10

  5. XM_024447770.1XP_024303538.1  sorbin and SH3 domain-containing protein 1 isoform X8

    Conserved Domains (4) summary
    cd11916
    Location:11231181
    SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11919
    Location:666720
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:740797
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    pfam02208
    Location:370411
    Sorb; Sorbin homologous domain
  6. XM_024447769.1XP_024303537.1  sorbin and SH3 domain-containing protein 1 isoform X5

    Conserved Domains (4) summary
    cd11916
    Location:12321290
    SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11919
    Location:775829
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:849906
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    pfam02208
    Location:370408
    Sorb; Sorbin homologous domain
  7. XM_017015510.2XP_016870999.1  sorbin and SH3 domain-containing protein 1 isoform X17

  8. XM_017015500.2XP_016870989.1  sorbin and SH3 domain-containing protein 1 isoform X4

  9. XM_017015505.2XP_016870994.1  sorbin and SH3 domain-containing protein 1 isoform X11

  10. XM_017015503.2XP_016870992.1  sorbin and SH3 domain-containing protein 1 isoform X9

  11. XM_017015501.2XP_016870990.1  sorbin and SH3 domain-containing protein 1 isoform X6

  12. XM_011539150.2XP_011537452.1  sorbin and SH3 domain-containing protein 1 isoform X2

    Conserved Domains (4) summary
    cd11916
    Location:14461504
    SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11919
    Location:9891043
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:10631120
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    pfam02208
    Location:609650
    Sorb; Sorbin homologous domain
  13. XM_017015507.2XP_016870996.1  sorbin and SH3 domain-containing protein 1 isoform X14

  14. XM_017015502.2XP_016870991.1  sorbin and SH3 domain-containing protein 1 isoform X7

  15. XM_011539140.2XP_011537442.1  sorbin and SH3 domain-containing protein 1 isoform X1

    Conserved Domains (4) summary
    cd11916
    Location:14711529
    SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11919
    Location:10141068
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:10881145
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    pfam02208
    Location:609647
    Sorb; Sorbin homologous domain
  16. XM_017015537.2XP_016871026.1  sorbin and SH3 domain-containing protein 1 isoform X44

  17. XM_017015532.2XP_016871021.1  sorbin and SH3 domain-containing protein 1 isoform X39

  18. XM_006717589.2XP_006717652.1  sorbin and SH3 domain-containing protein 1 isoform X22

    UniProtKB/Swiss-Prot
    Q9BX66
    Conserved Domains (4) summary
    cd11916
    Location:9451003
    SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11919
    Location:766820
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:840897
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cl02617
    Location:361399
    Sorb; Sorbin homologous domain
  19. XM_017015530.2XP_016871019.1  sorbin and SH3 domain-containing protein 1 isoform X37

  20. XM_017015517.2XP_016871006.1  sorbin and SH3 domain-containing protein 1 isoform X25

  21. XM_017015515.2XP_016871004.1  sorbin and SH3 domain-containing protein 1 isoform X23

  22. XM_017015539.1XP_016871028.1  sorbin and SH3 domain-containing protein 1 isoform X45

  23. XM_017015512.1XP_016871001.1  sorbin and SH3 domain-containing protein 1 isoform X19

  24. XM_017015540.1XP_016871029.1  sorbin and SH3 domain-containing protein 1 isoform X46

  25. XM_017015513.1XP_016871002.1  sorbin and SH3 domain-containing protein 1 isoform X20

  26. XM_017015514.1XP_016871003.1  sorbin and SH3 domain-containing protein 1 isoform X21

  27. XM_017015533.1XP_016871022.1  sorbin and SH3 domain-containing protein 1 isoform X40

  28. XM_011539167.1XP_011537469.1  sorbin and SH3 domain-containing protein 1 isoform X13

    Conserved Domains (4) summary
    cd11916
    Location:10821140
    SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11919
    Location:625679
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:699756
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    pfam02208
    Location:329370
    Sorb; Sorbin homologous domain
  29. XM_011539155.1XP_011537457.1  sorbin and SH3 domain-containing protein 1 isoform X3

    Conserved Domains (4) summary
    cd11916
    Location:13211379
    SH3_Sorbs1_3; Third (or C-terminal) Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11919
    Location:864918
    SH3_Sorbs1_1; First Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    cd11922
    Location:938995
    SH3_Sorbs1_2; Second Src Homology 3 domain of Sorbin and SH3 domain containing 1 (Sorbs1), also called ponsin
    pfam02208
    Location:568609
    Sorb; Sorbin homologous domain
  30. XM_017015509.1XP_016870998.1  sorbin and SH3 domain-containing protein 1 isoform X16

  31. XM_017015536.1XP_016871025.1  sorbin and SH3 domain-containing protein 1 isoform X43

  32. XM_017015525.1XP_016871014.1  sorbin and SH3 domain-containing protein 1 isoform X32

  33. XM_017015523.1XP_016871012.1  sorbin and SH3 domain-containing protein 1 isoform X30

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