Ppp1r3e protein phosphatase 1, regulatory subunit 3E [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ppp1r3eprovided by MGI
Official Full Name: protein phosphatase 1, regulatory subunit 3Eprovided by MGI
Primary source: MGI:MGI:2145790
See related: Ensembl:ENSMUSG00000072494 AllianceGenome:MGI:2145790
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm1211; A630071A11Rik
Summary: Predicted to enable [phosphorylase] phosphatase activity; glycogen binding activity; and protein phosphatase 1 binding activity. Predicted to contribute to phosphoprotein phosphatase activity. Predicted to be involved in positive regulation of glycogen biosynthetic process and regulation of glycogen catabolic process. Predicted to act upstream of or within glycogen metabolic process. Predicted to be located in glycogen granule. Predicted to be part of protein phosphatase type 1 complex. Orthologous to human PPP1R3E (protein phosphatase 1 regulatory subunit 3E). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in adrenal adult (RPKM 19.5), ovary adult (RPKM 15.7) and 24 other tissues See more
Orthologs: human all
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Genomic context

Location:: 14; 14 C3

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	14	NC_000080.7 (55113054..55114995, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	14	NC_000080.6 (54875597..54877538, complement)

Chromosome 14 - NC_000080.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

Homologs of the Ppp1r3e gene: The Ppp1r3e gene is conserved in human, chimpanzee, dog, cow, rat, and frog.
Orthologs from Annotation Pipeline: 254 organisms have orthologs with human gene Ppp1r3e
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables [phosphorylase] phosphatase activity	ISO Inferred from Sequence Orthology more info
enables glycogen binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed
contributes_to phosphoprotein phosphatase activity	ISO Inferred from Sequence Orthology more info
enables protein phosphatase 1 binding	IBA Inferred from Biological aspect of Ancestor more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glycogen metabolic process	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of glycogen biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in regulation of glycogen biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in regulation of glycogen biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in regulation of glycogen catabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in glycogen granule	ISO Inferred from Sequence Orthology more info
part_of protein phosphatase type 1 complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed

General protein information

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Preferred Names: protein phosphatase 1 regulatory subunit 3E

Names: protein phosphatase 1, regulatory (inhibitor) subunit 3E

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001167908.1 → NP_001161380.1 protein phosphatase 1 regulatory subunit 3E

Status: VALIDATED

Source sequence(s)

AC116591, BB645735

Consensus CDS

CCDS56958.1

UniProtKB/TrEMBL

H3BJB2

Related

ENSMUSP00000134915.2, ENSMUST00000168622.2

Conserved Domains (1) summary

pfam03370
Location:156 → 258

CBM_21; Carbohydrate/starch-binding module (family 21)