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LAMA4 laminin subunit alpha 4 [ Colobus angolensis palliatus ]

Gene ID: 105506752, updated on 13-Mar-2024

Summary

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Gene symbol
LAMA4
Gene description
laminin subunit alpha 4
See related
Ensembl:ENSCANG00000034417
Gene type
protein coding
RefSeq status
MODEL
Organism
Colobus angolensis palliatus (sub-species: palliatus)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Colobus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
39
Annotation release Status Assembly Chr Location
100 current Cang.pa_1.0 (GCF_000951035.1) Unplaced Scaffold NW_012114488.1 (17798158..17946512, complement)

NW_012114488.1Genomic Context describing neighboring genes Neighboring gene cellular communication network factor 6 Neighboring gene tubulin epsilon 1 Neighboring gene family with sequence similarity 229 member B Neighboring gene PIN2/TERF1-interacting telomerase inhibitor 1-like Neighboring gene ret finger protein like 4B

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012114488.1 Unplaced Scaffold Reference Cang.pa_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Colobus angolensis palliatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cang.pa_1.0

Genomic

  1. NW_012114488.1 Reference Cang.pa_1.0

    Range
    17798158..17946512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011935032.1 → XP_011790422.1  laminin subunit alpha-4 isoform X3

    UniProtKB/TrEMBL
    A0A2K5IZT6, A0A2K5IZX2
    Related
    ENSCANP00000022027.1, ENSCANT00000045006.1
    Conserved Domains (7) summary
    COG1340
    Location:419 → 717
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00055
    Location:187 → 238
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:1485 → 1617
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:289 → 545
    Laminin_I; Laminin Domain I
    pfam06009
    Location:727 → 854
    Laminin_II; Laminin Domain II
    cl02488
    Location:332 → 524
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl09111
    Location:503 → 602
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

  2. XM_011935031.1 → XP_011790421.1  laminin subunit alpha-4 isoform X2

    UniProtKB/TrEMBL
    A0A2K5IZX2
    Conserved Domains (7) summary
    COG1340
    Location:501 → 799
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00055
    Location:269 → 320
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:1567 → 1699
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:371 → 627
    Laminin_I; Laminin Domain I
    pfam06009
    Location:809 → 936
    Laminin_II; Laminin Domain II
    cl02488
    Location:414 → 606
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl09111
    Location:585 → 684
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

  3. XM_011935030.1 → XP_011790420.1  laminin subunit alpha-4 isoform X1

    UniProtKB/TrEMBL
    A0A2K5IZX2
    Conserved Domains (7) summary
    COG1340
    Location:508 → 806
    COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]
    cd00055
    Location:269 → 320
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:1574 → 1706
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:378 → 634
    Laminin_I; Laminin Domain I
    pfam06009
    Location:816 → 943
    Laminin_II; Laminin Domain II
    cl02488
    Location:421 → 613
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl09111
    Location:592 → 691
    Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
Nucleotide Protein
Heading Accession and Version

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