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PPIAL4H peptidylprolyl isomerase A like 4H [ Homo sapiens (human) ]

Gene ID: 105371242, updated on 23-Nov-2023

Summary

Official Symbol
PPIAL4Hprovided by HGNC
Official Full Name
peptidylprolyl isomerase A like 4Hprovided by HGNC
Primary source
HGNC:HGNC:53889
See related
Ensembl:ENSG00000270339 AllianceGenome:HGNC:53889
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See PPIAL4H in Genome Data Viewer
Location:
1q21.1
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (146344006..146344765, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (148463605..148464364)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 (PATCHES) NW_003871055.3 (3159419..3160178, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 1071, pseudogene Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:145140047-145140919 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:145139173-145140046 Neighboring gene nudix hydrolase 4 pseudogene 2 Neighboring gene SEC22 homolog B4, pseudogene Neighboring gene tRNA-Asn (anticodon GTT) 24-1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1276 Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC112268274

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables cyclosporin A binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables peptidyl-prolyl cis-trans isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in protein folding IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein peptidyl-prolyl isomerization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
peptidyl-prolyl cis-trans isomerase A-like 4H
Names
PPIase A-like 4H
peptidyl-prolyl cis-trans isomerase A-like 4C
NP_001355057.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368128.3NP_001355057.1  peptidyl-prolyl cis-trans isomerase A-like 4H

    Status: VALIDATED

    Source sequence(s)
    AC243756
    Consensus CDS
    CCDS91036.1
    UniProtKB/Swiss-Prot
    A0A075B767
    UniProtKB/TrEMBL
    A0A0H2UH34
    Related
    ENSP00000464619.2, ENST00000584068.4

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    146344006..146344765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    148463605..148464364
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)