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CLDN14-AS1 CLDN14 antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 105369301, updated on 4-Mar-2025

Summary

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Official Symbol
CLDN14-AS1provided by HGNC
Official Full Name
CLDN14 antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:55953
See related
Ensembl:ENSG00000230479 AllianceGenome:HGNC:55953
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PTAR
Expression
Low expression observed in reference dataset See more
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Genomic context

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See CLDN14-AS1 in Genome Data Viewer
Location:
21q22.13
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (36430325..36498526)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (34812904..34880646)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (37802623..37870824)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13284 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:37708895-37710094 Neighboring gene MORC family CW-type zinc finger 3 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:37737075-37737251 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13285 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13286 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:37758141-37758642 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:37758643-37759142 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:37780832-37782031 Neighboring gene ATP synthase membrane subunit f pseudogene 1 Neighboring gene chromatin assembly factor 1 subunit B Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:37802462-37803337 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18434 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:37836794-37837391 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:37842779-37843278 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18435 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18436 Neighboring gene claudin 14 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18437 Neighboring gene proteasome 26S subunit, non-ATPase 4 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13287 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18438 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18439 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13288 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18440 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:37973046-37973546 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:37973547-37974047 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:37978989-37979489 Neighboring gene uncharacterized LOC105369308 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:38031419-38031920 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:38031921-38032420 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr21:38067894-38068806 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:38072642-38073235 Neighboring gene uncharacterized LOC107985492 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:38073236-38073828 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:38077313-38078142 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:38078973-38079802 Neighboring gene SIM bHLH transcription factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Bibliography

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Related articles in PubMed

  1. Long non-coding RNA lnc-CHAF1B-3 promotes renal interstitial fibrosis by regulating EMT-related genes in renal proximal tubular cells. Imai K, et al. Mol Ther Nucleic Acids, 2023 Mar 14. PMID 36700051, Free PMC Article
  2. LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression. Liang H, et al. Mol Cancer, 2018 Aug 11. PMID 30098599, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

General gene information

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Other Names

  • claudin 14 antisense RNA 1
  • lnc-CHAF1B-3
  • pro-transition associated RNA

Clone Names

  • AP000695.4, AP000695.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_183529.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000694, AP000695

  2. NR_183530.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000694, AP000695

  3. NR_183531.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000694, AP000695

  4. NR_183532.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000694, AP000695
    Related
    ENST00000820008.1

  5. NR_183533.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000694

  6. NR_183534.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000694

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    36430325..36498526
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    34812904..34880646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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