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Tedc1 tubulin epsilon and delta complex 1 [ Mus musculus (house mouse) ]

Gene ID: 104732, updated on 26-Sep-2022

Summary

Official Symbol
Tedc1provided by MGI
Official Full Name
tubulin epsilon and delta complex 1provided by MGI
Primary source
MGI:MGI:2144738
See related
Ensembl:ENSMUSG00000037466 AllianceGenome:MGI:2144738
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mFLJ00116; 4930427A07Rik
Summary
Involved in positive regulation of smoothened signaling pathway. Located in centriole and cilium. Orthologous to human TEDC1 (tubulin epsilon and delta complex 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in thymus adult (RPKM 12.7), testis adult (RPKM 11.0) and 20 other tissues See more
Orthologs
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Genomic context

See Tedc1 in Genome Data Viewer
Location:
12; 12 F1
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (113118639..113135102)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (113156421..113165458)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30599 Neighboring gene cysteine-rich protein 1 (intestinal) Neighboring gene origin of replication downstream of immunoglobulin heavy chain (Igh) locus Neighboring gene transmembrane protein 121

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ00116

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in positive regulation of smoothened signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
located_in centriole IDA
Inferred from Direct Assay
more info
PubMed 
located_in cilium IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
tubulin epsilon and delta complex protein 1
Names
uncharacterized protein C14orf80 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134041.3NP_598802.2  tubulin epsilon and delta complex protein 1

    See identical proteins and their annotated locations for NP_598802.2

    Status: VALIDATED

    Source sequence(s)
    AK167092, BB615126, BI134858
    Consensus CDS
    CCDS49196.1
    UniProtKB/Swiss-Prot
    Q3TK97, Q3UK37
    Related
    ENSMUSP00000035351.9, ENSMUST00000049271.13
    Conserved Domains (3) summary
    COG0841
    Location:285382
    AcrB; Multidrug efflux pump subunit AcrB [Defense mechanisms]
    pfam14970
    Location:41221
    DUF4509; Domain of unknown function (DUF4509)
    pfam14971
    Location:266418
    DUF4510; Domain of unknown function (DUF4510)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    113118639..113135102
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036157146.1XP_036013039.1  tubulin epsilon and delta complex protein 1 isoform X1

    Conserved Domains (2) summary
    pfam14970
    Location:156
    DUF4509; Domain of unknown function (DUF4509)
    pfam14971
    Location:101253
    DUF4510; Domain of unknown function (DUF4510)
  2. XM_036157147.1XP_036013040.1  tubulin epsilon and delta complex protein 1 isoform X1

    Conserved Domains (2) summary
    pfam14970
    Location:156
    DUF4509; Domain of unknown function (DUF4509)
    pfam14971
    Location:101253
    DUF4510; Domain of unknown function (DUF4510)