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ZNHIT1 zinc finger HIT-type containing 1 [ Homo sapiens (human) ]

Gene ID: 10467, updated on 5-Apr-2020

Summary

Official Symbol
ZNHIT1provided by HGNC
Official Full Name
zinc finger HIT-type containing 1provided by HGNC
Primary source
HGNC:HGNC:21688
See related
Ensembl:ENSG00000106400 MIM:618617
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CG1I; ZNFN4A1
Expression
Ubiquitous expression in liver (RPKM 23.5), kidney (RPKM 21.2) and 25 other tissues See more
Orthologs

Genomic context

See ZNHIT1 in Genome Data Viewer
Location:
7q22.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (101218165..101224191)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (100860985..100867471)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ribosomal protein SA pseudogene 46 Neighboring gene procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 Neighboring gene claudin 15 Neighboring gene fission, mitochondrial 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
histone exchange IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of histone deacetylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
zinc finger HIT domain-containing protein 1
Names
H_DJ0747G18.14
cyclin-G1-binding protein 1
p18 Hamlet
p18Hamlet
putative cyclin G1 interacting protein
zinc finger protein subfamily 4A member 1
zinc finger protein, subfamily 4A (HIT domain containing), member 1
zinc finger, HIT domain containing 1
zinc finger, HIT type 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_006349.3NP_006340.1  zinc finger HIT domain-containing protein 1

    See identical proteins and their annotated locations for NP_006340.1

    Status: VALIDATED

    Source sequence(s)
    BC001877, BC017333
    Consensus CDS
    CCDS5716.1
    UniProtKB/Swiss-Prot
    O43257
    Related
    ENSP00000304593.2, ENST00000305105.3
    Conserved Domains (2) summary
    cl02154
    Location:75135
    YL1_C; YL1 nuclear protein C-terminal domain
    pfam04438
    Location:113140
    zf-HIT; HIT zinc finger

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    101218165..101224191
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011515739.2XP_011514041.1  zinc finger HIT domain-containing protein 1 isoform X1

    Conserved Domains (2) summary
    pfam04438
    Location:128155
    zf-HIT; HIT zinc finger
    cl02154
    Location:90150
    YL1_C; YL1 nuclear protein C-terminal domain
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