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TNF tumor necrosis factor [ Rhinopithecus roxellana (golden snub-nosed monkey) ]

Gene ID: 104661913, updated on 12-Mar-2024

Summary

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Gene symbol
TNF
Gene description
tumor necrosis factor
See related
Ensembl:ENSRROG00000021663
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinopithecus roxellana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
4
Annotation release Status Assembly Chr Location
101 current ASM756505v1 (GCF_007565055.1) 4 NC_044552.1 (25134100..25136912)
100 previous assembly Rrox_v1 (GCF_000769185.1) Unplaced Scaffold NW_010798269.1 (119005..121791)

Chromosome 4 - NC_044552.1Genomic Context describing neighboring genes Neighboring gene NFKB inhibitor like 1 Neighboring gene 2-iminobutanoate/2-iminopropanoate deaminase pseudogene Neighboring gene uncharacterized LOC115896975 Neighboring gene lymphotoxin alpha Neighboring gene uncharacterized LOC115896875 Neighboring gene lymphotoxin beta Neighboring gene leukocyte specific transcript 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CD40 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tumor necrosis factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinopithecus roxellana Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM756505v1 Primary Assembly

Genomic

  1. NC_044552.1 Reference ASM756505v1 Primary Assembly

    Range
    25134100..25136912
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010362752.2 → XP_010361054.1  tumor necrosis factor isoform X1

    UniProtKB/TrEMBL
    A0A2K6NLV2
    Conserved Domains (1) summary
    pfam00229
    Location:104 → 234
    TNF; TNF(tumor Necrosis Factor) family

  2. XM_010362753.2 → XP_010361055.1  tumor necrosis factor isoform X2

    See identical proteins and their annotated locations for XP_010361055.1

    UniProtKB/TrEMBL
    A0A2K6NLU3, A0A2K6NLV2
    Related
    ENSRROP00000005240.1
    Conserved Domains (1) summary
    pfam00229
    Location:103 → 233
    TNF; TNF(tumor Necrosis Factor) family
Nucleotide Protein
Heading Accession and Version

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