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CD52 CD52 molecule [ Homo sapiens (human) ]

Gene ID: 1043, updated on 1-Jun-2020

Summary

Official Symbol
CD52provided by HGNC
Official Full Name
CD52 moleculeprovided by HGNC
Primary source
HGNC:HGNC:1804
See related
Ensembl:ENSG00000169442 MIM:114280
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HE5; CDW52; EDDM5
Expression
Biased expression in lymph node (RPKM 265.0), spleen (RPKM 195.7) and 9 other tissues See more
Orthologs

Genomic context

See CD52 in Genome Data Viewer
Location:
1p36.11
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (26317958..26320523)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (26644411..26647014)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene centrosomal protein 85 Neighboring gene mitochondrial ribosomal protein S6 pseudogene 1 Neighboring gene SH3 domain binding glutamate rich protein like 3 Neighboring gene UBX domain protein 11 Neighboring gene crystallin beta-gamma domain containing 2 Neighboring gene ribosomal protein L34 pseudogene 4 Neighboring gene zinc finger protein 683

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
positive regulation of cytosolic calcium ion concentration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of cytosolic calcium ion concentration IDA
Inferred from Direct Assay
more info
PubMed 
respiratory burst NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
anchored component of membrane IEA
Inferred from Electronic Annotation
more info
 
cell IEA
Inferred from Electronic Annotation
more info
 
extracellular region TAS
Traceable Author Statement
more info
 
intrinsic component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
membrane TAS
Traceable Author Statement
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 
sperm midpiece IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
CAMPATH-1 antigen
Names
CD52 antigen (CAMPATH-1 antigen)
CDW52 antigen (CAMPATH-1 antigen)
HEL-S-171mP
cambridge pathology 1 antigen
epididymal secretory protein E5
epididymis secretory sperm binding protein Li 171mP
human epididymis-specific protein 5

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001803.3NP_001794.2  CAMPATH-1 antigen precursor

    See identical proteins and their annotated locations for NP_001794.2

    Status: VALIDATED

    Source sequence(s)
    BC000644, BI835519, X62466
    Consensus CDS
    CCDS30647.1
    UniProtKB/Swiss-Prot
    P31358
    UniProtKB/TrEMBL
    V9HWN9
    Related
    ENSP00000363330.2, ENST00000374213.3

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    26317958..26320523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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