Format

Send to:

Choose Destination

UBAC1 UBA domain containing 1 [ Homo sapiens (human) ]

Gene ID: 10422, updated on 21-Jan-2020

Summary

Official Symbol
UBAC1provided by HGNC
Official Full Name
UBA domain containing 1provided by HGNC
Primary source
HGNC:HGNC:30221
See related
Ensembl:ENSG00000130560 MIM:608129
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KPC2; GBDR1; UBADC1
Expression
Ubiquitous expression in bone marrow (RPKM 32.5), testis (RPKM 24.1) and 25 other tissues See more
Orthologs

Genomic context

See UBAC1 in Genome Data Viewer
Location:
9q34.3
Exon count:
10
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (135932969..135961373, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (138824815..138853226, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene calmodulin regulated spectrin associated protein 1 Neighboring gene Sharpr-MPRA regulatory region 8889 Neighboring gene uncharacterized LOC107987141 Neighboring gene uncharacterized LOC105376322 Neighboring gene NACC family member 2 Neighboring gene long intergenic non-protein coding RNA 2846

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
 
cytosol IDA
Inferred from Direct Assay
more info
 
extracellular exosome HDA PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
ubiquitin-associated domain-containing protein 1
Names
E3 ubiquitin-protein ligase subunit KPC2
Kip1 ubiquitination-promoting complex subunit 2
UBA domain-containing protein 1
glialblastoma cell differentiation-related protein 1
kip1 ubiquitination-promoting complex protein 2
putative glialblastoma cell differentiation-related protein
testicular secretory protein Li 64
ubiquitin associated domain containing 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016172.3NP_057256.2  ubiquitin-associated domain-containing protein 1

    See identical proteins and their annotated locations for NP_057256.2

    Status: VALIDATED

    Source sequence(s)
    AL355574
    Consensus CDS
    CCDS35177.1
    UniProtKB/Swiss-Prot
    Q9BSL1
    UniProtKB/TrEMBL
    A0A140VK64
    Related
    ENSP00000360821.3, ENST00000371756.4
    Conserved Domains (3) summary
    smart00727
    Location:353392
    STI1; Heat shock chaperonin-binding motif
    cd14303
    Location:195232
    UBA1_KPC2; UBA1 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
    cd14304
    Location:290327
    UBA2_KPC2; UBA2 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    135932969..135961373 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center