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CDR2 cerebellar degeneration related protein 2 [ Homo sapiens (human) ]

Gene ID: 1039, updated on 5-Mar-2024

Summary

Official Symbol
CDR2provided by HGNC
Official Full Name
cerebellar degeneration related protein 2provided by HGNC
Primary source
HGNC:HGNC:1799
See related
Ensembl:ENSG00000140743 MIM:117340; AllianceGenome:HGNC:1799
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Yo; CDR62
Summary
Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 38.3), thyroid (RPKM 28.3) and 24 other tissues See more
Orthologs
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Genomic context

See CDR2 in Genome Data Viewer
Location:
16p12.2
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (22345936..22374619, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (21842595..21871275)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (22357257..22385940, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:22308474-22309018 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10570 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7267 Neighboring gene tRNA-Leu (anticodon AAG) 2-4 Neighboring gene Sharpr-MPRA regulatory region 3906 Neighboring gene RNA polymerase III subunit E Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:22333033-22333580 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:22333581-22334130 Neighboring gene uncharacterized LOC124903664 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:22358198-22358698 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10571 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7268 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7269 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10572 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10573 Neighboring gene CDR2 divergent transcript Neighboring gene major facilitator superfamily domain containing 13B (pseudogene)

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cerebellar degeneration-related protein 2
Names
Yo paraneoplastic antigen
cerebellar degeneration-related protein 2, 62kDa
major Yo paraneoplastic antigen
paraneoplastic cerebellar degeneration-associated antigen

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001802.2NP_001793.1  cerebellar degeneration-related protein 2

    See identical proteins and their annotated locations for NP_001793.1

    Status: VALIDATED

    Source sequence(s)
    AC092338, BC017503, BG386156, BG750955, BM714067, CB990819, M63256
    Consensus CDS
    CCDS32404.1
    UniProtKB/Swiss-Prot
    A8K8A8, Q01850, Q13977
    Related
    ENSP00000268383.2, ENST00000268383.7
    Conserved Domains (1) summary
    TIGR02168
    Location:8263
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    22345936..22374619 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024450143.2XP_024305911.1  cerebellar degeneration-related protein 2 isoform X1

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_017852933.1 Reference GRCh38.p14 PATCHES

    Range
    730420..759098
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054332139.1XP_054188114.1  cerebellar degeneration-related protein 2 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    21842595..21871275
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054379386.1XP_054235361.1  cerebellar degeneration-related protein 2 isoform X1