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Hoxb2 homeobox B2 [ Mus musculus (house mouse) ]

Gene ID: 103889, updated on 3-Jun-2018
Official Symbol
Hoxb2provided by MGI
Official Full Name
homeobox B2provided by MGI
Primary source
MGI:MGI:96183
See related
Ensembl:ENSMUSG00000075588 Vega:OTTMUSG00000001779
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hox-2.8; Hoxbes2; AI894218
Expression
Broad expression in adrenal adult (RPKM 30.9), genital fat pad adult (RPKM 12.5) and 15 other tissues See more
Orthologs
See Hoxb2 in Genome Data Viewer
Location:
11 D; 11 59.85 cM
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (96351632..96354020)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (96212946..96215330)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene homeobox B3 Neighboring gene microRNA 10a Neighboring gene homeobox B4 Neighboring gene homeobox B3 and homeobox B2, opposite strand Neighboring gene homeobox B1 Neighboring gene ribosomal protein L17 pseudogene

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II proximal promoter sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
anterior/posterior pattern specification IGI
Inferred from Genetic Interaction
more info
PubMed 
anterior/posterior pattern specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal/ventral pattern formation IGI
Inferred from Genetic Interaction
more info
PubMed 
embryonic skeletal system morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
facial nerve structural organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
morphogenesis of an epithelial sheet IGI
Inferred from Genetic Interaction
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
neural nucleus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
rhombomere 3 development IGI
Inferred from Genetic Interaction
more info
PubMed 
rhombomere 4 development IGI
Inferred from Genetic Interaction
more info
PubMed 
skeletal system morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
skeletal system morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
nuclear speck ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
homeobox protein Hox-B2
Names
homeo box B2
homeobox protein Hox-2.8

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134032.2NP_598793.2  homeobox protein Hox-B2

    See identical proteins and their annotated locations for NP_598793.2

    Status: VALIDATED

    Source sequence(s)
    AI893165, AL606824
    Consensus CDS
    CCDS36290.1
    UniProtKB/Swiss-Prot
    P0C1T1
    Related
    ENSMUSP00000098092.4, OTTMUSP00000001717, ENSMUST00000100523.6, OTTMUST00000003569
    Conserved Domains (1) summary
    pfam00046
    Location:145197
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

    Range
    96351632..96354020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531932.3XP_006531995.1  homeobox protein Hox-B2 isoform X1

    Conserved Domains (1) summary
    pfam00046
    Location:2375
    Homeobox; Homeobox domain
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