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CDR1 cerebellar degeneration related 1 [ Homo sapiens (human) ]

Gene ID: 1038, updated on 17-Sep-2024

Summary

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Official Symbol
CDR1provided by HGNC
Official Full Name
cerebellar degeneration related 1provided by HGNC
Primary source
HGNC:HGNC:1798
See related
MIM:302650; AllianceGenome:HGNC:1798
Gene type
unknown
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CDR; CDR34; CDR62A
Orthologs
all

Genomic context

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Location:
Xq27.1
Annotation release Status Assembly Chr Location
RS_2023_10 latest, but not current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (140772083..140793212, complement)
RS_2023_10 latest, but not current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (139089454..139110579, complement)

Bibliography

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Related articles in PubMed

  1. Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis. Wang LL, et al. Curr Med Sci, 2020 Jun. PMID 32681261
  2. Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in Alzheimer's disease. Bosco P, et al. Neurol Sci, 2014 Oct. PMID 24777548
  3. Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in prostate cancer cell lines. Salemi M, et al. Int J Biol Markers, 2014 Sep 30. PMID 24366849
  4. The tolerogenic peptide, hCDR1, down-regulates the expression of interferon-α in murine and human systemic lupus erythematosus. Sthoeger Z, et al. PLoS One, 2013. PMID 23555966, Free PMC Article
  5. Cloning of a brain protein identified by autoantibodies from a patient with paraneoplastic cerebellar degeneration. Dropcho EJ, et al. Proc Natl Acad Sci U S A, 1987 Jul. PMID 3474619, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis.
    Title: Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis.
  2. Our study confirmed that the circ_0001946/miR-671-5p/ CDR1 pathway modulates the development of glioblastoma
    Title: Circular RNA circ_0001946 acts as a competing endogenous RNA to inhibit glioblastoma progression by modulating miR-671-5p and CDR1.
  3. Underexpression of CDR1 is associated with glioblastoma multiforme.
    Title: Dysregulated miR-671-5p / CDR1-AS / CDR1 / VSNL1 axis is involved in glioblastoma multiforme.
  4. The results of this case-control study showed that the CDR1 gene was over-expressed in five out of seven subjects with AD compared to seven age- and sex-matched normal controls. Data suggest that CDR1 gene may play a role, in Alzheimer's disease process.
    Title: Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in Alzheimer's disease.
  5. The CDR1 gene was overexpressed in the LNCaP and PC-3 PCa cell lines as compared with the PNT1A normal prostate cell line.
    Title: Cerebellar degeneration-related autoantigen 1 (CDR1) gene expression in prostate cancer cell lines.
  6. Treatment of systemic lupus erythematosus afflicted (NZBxNZW)F1 mice with human CDR1 down regulated gene expression of IFN-alpha.
    Title: The tolerogenic peptide, hCDR1, down-regulates the expression of interferon-α in murine and human systemic lupus erythematosus.
  7. miR-671 directs cleavage of a circular antisense transcript of the Cerebellar Degeneration-Related protein 1 (CDR1) locus in an Ago2-slicer-dependent manner.
    Title: miRNA-dependent gene silencing involving Ago2-mediated cleavage of a circular antisense RNA.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Other Names

  • cerebellar degeneration related protein 1
  • cerebellar degeneration-related antigen 1
  • cerebellar degeneration-related protein 1, 34kDa

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_016361.1: Suppressed sequence

    Description
    NG_016361.1: This RefSeq was removed by NCBI staff.

  2. NM_004065.2: Suppressed sequence

    Description
    NM_004065.2: This RefSeq was removed because it is now thought that this gene does not encode a protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P51861.2 GenPept UniProtKB/Swiss-Prot:P51861

Gene LinkOut

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