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Dnaaf10 dynein axonemal assembly factor 10 [ Mus musculus (house mouse) ]

Gene ID: 103784, updated on 5-Mar-2024

Summary

Official Symbol
Dnaaf10provided by MGI
Official Full Name
dynein axonemal assembly factor 10provided by MGI
Primary source
MGI:MGI:2144224
See related
Ensembl:ENSMUSG00000078970 AllianceGenome:MGI:2144224
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HZGJ; Wdr92
Summary
Predicted to enable ubiquitin binding activity. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytoplasm. Orthologous to human DNAAF10 (dynein axonemal assembly factor 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 3.6), placenta adult (RPKM 3.4) and 28 other tissues See more
Orthologs
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Genomic context

Location:
11 A2; 11 9.75 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (17161893..17185200)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (17211893..17235200)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) Neighboring gene STARR-seq mESC enhancer starr_28704 Neighboring gene STARR-positive B cell enhancer ABC_E3933 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:17111656-17111843 Neighboring gene partner of NOB1 homolog Neighboring gene STARR-seq mESC enhancer starr_28705 Neighboring gene C1D nuclear receptor co-repressor Neighboring gene aldo-keto reductase family 1, member B3 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: Ppp3r1

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ubiquitin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of RPAP3/R2TP/prefoldin-like complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
dynein axonemal assembly factor 10
Names
WD repeat domain 92
WD repeat-containing protein 92
WD repeat-containing protein Monad

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178909.4NP_849240.1  dynein axonemal assembly factor 10

    See identical proteins and their annotated locations for NP_849240.1

    Status: VALIDATED

    Source sequence(s)
    AK033294, AL713926, BY794211
    Consensus CDS
    CCDS24450.1
    UniProtKB/Swiss-Prot
    Q8BGF3
    Related
    ENSMUSP00000040938.7, ENSMUST00000046955.7
    Conserved Domains (3) summary
    COG2319
    Location:2348
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:2164
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:21348
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    17161893..17185200
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)