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Pnpo pyridoxine 5'-phosphate oxidase [ Mus musculus (house mouse) ]

Gene ID: 103711, updated on 19-Mar-2019

Summary

Official Symbol
Pnpoprovided by MGI
Official Full Name
pyridoxine 5'-phosphate oxidaseprovided by MGI
Primary source
MGI:MGI:2144151
See related
Ensembl:ENSMUSG00000018659
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AI415282
Expression
Biased expression in liver E14.5 (RPKM 227.8), liver E14 (RPKM 217.6) and 14 other tissues See more
Orthologs

Genomic context

See Pnpo in Genome Data Viewer
Location:
11; 11 D
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (96937816..96944019, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (96799130..96805333, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene CDK5 regulatory subunit associated protein 3 Neighboring gene predicted gene 11525 Neighboring gene proline rich 15-like Neighboring gene RIKEN cDNA D030028A08 gene Neighboring gene Sp2 transcription factor Neighboring gene predicted gene, 30809

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
FMN binding ISO
Inferred from Sequence Orthology
more info
 
cofactor binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on the CH-NH2 group of donors IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
pyridoxal phosphate binding ISO
Inferred from Sequence Orthology
more info
 
pyridoxamine-phosphate oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
pyridoxamine-phosphate oxidase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
pyridoxal phosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
pyridoxal phosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
pyridoxine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
pyridoxine-5'-phosphate oxidase
Names
pyridoxamine-phosphate oxidase
NP_598782.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_134021.2NP_598782.1  pyridoxine-5'-phosphate oxidase

    See identical proteins and their annotated locations for NP_598782.1

    Status: VALIDATED

    Source sequence(s)
    AI464320, AK164667, AL596384, CK625276
    Consensus CDS
    CCDS25308.1
    UniProtKB/Swiss-Prot
    Q91XF0
    Related
    ENSMUSP00000018803.5, ENSMUST00000018803.11
    Conserved Domains (3) summary
    TIGR00558
    Location:57261
    pdxH; pyridoxamine-phosphate oxidase
    pfam01243
    Location:75153
    Pyridox_oxidase; Pyridoxamine 5'-phosphate oxidase
    pfam10590
    Location:206261
    PNPOx_C; Pyridoxine 5'-phosphate oxidase C-terminal dimerization region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

    Range
    96937816..96944019 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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