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setdb2 SET domain bifurcated histone lysine methyltransferase 2 [ Cynoglossus semilaevis (tongue sole) ]

Gene ID: 103389803, updated on 11-Mar-2024

Summary

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Gene symbol
setdb2
Gene description
SET domain bifurcated histone lysine methyltransferase 2
See related
Ensembl:ENSCSEG00000008574
Gene type
protein coding
RefSeq status
MODEL
Organism
Cynoglossus semilaevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
Orthologs
zebrafish all
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Genomic context

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See setdb2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
13
Annotation release Status Assembly Chr Location
102 current Cse_v1.0 (GCF_000523025.1) 14 NC_024320.1 (16178153..16184216)

Chromosome 14 - NC_024320.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112488062 Neighboring gene zinc finger protein ZFMSA12A-like Neighboring gene prothrombin Neighboring gene uncharacterized LOC103389804 Neighboring gene cellular repressor of E1A-stimulated genes 1 Neighboring gene CD247 molecule

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024320.1 Chromosome 14 Reference Cse_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H3K9 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heterochromatin organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA methylation-dependent heterochromatin formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase SETDB2
Names
SET domain bifurcated 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cynoglossus semilaevis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cse_v1.0 Primary Assembly

Genomic

  1. NC_024320.1 Reference Cse_v1.0 Primary Assembly

    Range
    16178153..16184216
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025062428.1 → XP_024918196.1  histone-lysine N-methyltransferase SETDB2 isoform X2

    Conserved Domains (3) summary
    smart00317
    Location:300 → 511
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    pfam05033
    Location:191 → 292
    Pre-SET; Pre-SET motif
    cl00110
    Location:103 → 170
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...

  2. XM_017038386.2 → XP_016893875.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    UniProtKB/TrEMBL
    A0A3P8VD86
    Related
    ENSCSEP00000013288.1, ENSCSET00000013446.1
    Conserved Domains (3) summary
    smart00317
    Location:350 → 561
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    pfam05033
    Location:241 → 342
    Pre-SET; Pre-SET motif
    cl00110
    Location:153 → 220
    MBD; MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...
Nucleotide Protein
Heading Accession and Version

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