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LOC103005791 calpain-3 [ Balaenoptera acutorostrata (minke whale) ]

Gene ID: 103005791, updated on 3-Apr-2024

Summary

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Gene symbol
LOC103005791
Gene description
calpain-3
Gene type
protein coding
RefSeq status
MODEL
Organism
Balaenoptera acutorostrata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti; Balaenopteridae; Balaenoptera
Also known as
GANC; CAPN3
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Genomic context

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Location:
chromosome: 3
Exon count:
50
Annotation release Status Assembly Chr Location
RS_2023_06 current mBalAcu1.1 (GCF_949987535.1) 3 NC_080066.1 (94708953..94837655, complement)
101 previous assembly BalAcu1.0 (GCF_000493695.1) Unplaced Scaffold NW_006725954.1 (3615329..3746610, complement)

Chromosome 3 - NC_080066.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 23 Neighboring gene zinc finger protein 106 Neighboring gene uncharacterized LOC130707767 Neighboring gene transmembrane protein 87A Neighboring gene COP9 signalosome complex subunit 7a-like Neighboring gene VPS39 subunit of HOPS complex

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha-1,4-glucosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in N-glycan processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3; neutral alpha-glucosidase C; uncharacterized protein LOC103005791
Names
glucosidase, alpha; neutral C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_949987535.1-RS_2023_06

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mBalAcu1.1

Genomic

  1. NC_080066.1 Reference mBalAcu1.1

    Range
    94708953..94837655 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_057544756.1 → XP_057400739.1  neutral alpha-glucosidase C isoform X4

  2. XM_057544755.1 → XP_057400738.1  neutral alpha-glucosidase C isoform X3

  3. XM_007173607.3 → XP_007173669.2  neutral alpha-glucosidase C isoform X2

    UniProtKB/TrEMBL
    A0A383ZFN0, A0A452CAL2
    Conserved Domains (6) summary
    cd06603
    Location:353 → 820
    GH31_GANC_GANAB_alpha; neutral alpha-glucosidase C, neutral alpha-glucosidase AB
    cd14752
    Location:213 → 353
    GH31_N; N-terminal domain of glycosyl hydrolase family 31 (GH31)
    pfam16648
    Location:1356 → 1426
    Calpain_u2; Unstructured region on Calpain-3
    cd16190
    Location:1426 → 1594
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:875 → 1188
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:1209 → 1352
    Calpain_III; Calpain large subunit, domain III

  4. XM_028164356.2 → XP_028020157.1  neutral alpha-glucosidase C isoform X1

    UniProtKB/TrEMBL
    A0A452CAL2, A0A452CAR0
    Conserved Domains (6) summary
    cd06603
    Location:354 → 821
    GH31_GANC_GANAB_alpha; neutral alpha-glucosidase C, neutral alpha-glucosidase AB
    cd14752
    Location:214 → 354
    GH31_N; N-terminal domain of glycosyl hydrolase family 31 (GH31)
    pfam16648
    Location:1357 → 1427
    Calpain_u2; Unstructured region on Calpain-3
    cd16190
    Location:1427 → 1595
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:876 → 1189
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:1210 → 1353
    Calpain_III; Calpain large subunit, domain III

  5. XM_028164359.2 → XP_028020160.1  uncharacterized protein LOC103005791 isoform X5

    UniProtKB/TrEMBL
    A0A452CAL2, A0A452CB43
    Conserved Domains (6) summary
    cd06603
    Location:204 → 671
    GH31_GANC_GANAB_alpha; neutral alpha-glucosidase C, neutral alpha-glucosidase AB
    cd14752
    Location:64 → 204
    GH31_N; N-terminal domain of glycosyl hydrolase family 31 (GH31)
    pfam16648
    Location:1207 → 1277
    Calpain_u2; Unstructured region on Calpain-3
    cd16190
    Location:1277 → 1445
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:726 → 1039
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:1060 → 1203
    Calpain_III; Calpain large subunit, domain III

  6. XM_007173615.3 → XP_007173677.1  calpain-3 isoform X7

    UniProtKB/TrEMBL
    A0A383ZF25
    Conserved Domains (5) summary
    cd00051
    Location:698 → 752
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00648
    Location:75 → 416
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:430 → 580
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:584 → 654
    Calpain_u2; Unstructured region on Calpain-3
    cl08302
    Location:729 → 818
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

  7. XM_028164360.2 → XP_028020161.1  calpain-3 isoform X8

    UniProtKB/TrEMBL
    A0A452CB93
    Conserved Domains (4) summary
    pfam16648
    Location:245 → 315
    Calpain_u2; Unstructured region on Calpain-3
    cd16190
    Location:315 → 483
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam01067
    Location:98 → 241
    Calpain_III; Calpain large subunit, domain III
    cl00051
    Location:13 → 87
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.

  8. XM_007173614.3 → XP_007173676.1  neutral alpha-glucosidase C isoform X6

    UniProtKB/TrEMBL
    A0A383ZF14
    Conserved Domains (3) summary
    cd06603
    Location:353 → 820
    GH31_GANC_GANAB_alpha; neutral alpha-glucosidase C, neutral alpha-glucosidase AB
    cd14752
    Location:213 → 353
    GH31_N; N-terminal domain of glycosyl hydrolase family 31 (GH31)
    pfam01055
    Location:334 → 779
    Glyco_hydro_31; Glycosyl hydrolases family 31

  9. XM_057544757.1 → XP_057400740.1  neutral alpha-glucosidase C isoform X9

RNA

  1. XR_009007794.1 RNA Sequence

  2. XR_009007795.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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