U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CORIN corin, serine peptidase [ Panthera tigris (tiger) ]

Gene ID: 102968431, updated on 15-Nov-2024

Summary

Go to the top of the page Help
Gene symbol
CORIN
Gene description
corin, serine peptidase
See related
Ensembl:ENSPTIG00000020309
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CORIN in Genome Data Viewer
Location:
chromosome: B1
Exon count:
24
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) B1 NC_056663.1 (164098937..164350098)
101 previous assembly PanTig1.0 (GCF_000464555.1) Unplaced Scaffold NW_006711756.1 (2642104..2893854)

Chromosome B1 - NC_056663.1Genomic Context describing neighboring genes Neighboring gene cyclic nucleotide gated channel subunit alpha 1 Neighboring gene nuclear transcription factor, X-box binding like 1 Neighboring gene 40S ribosomal protein S4, X isoform-like Neighboring gene U6 spliceosomal RNA Neighboring gene NIF3-like protein 1 Neighboring gene ATPase phospholipid transporting 10D (putative) Neighboring gene uncharacterized LOC122238047 Neighboring gene COMM domain containing 8 Neighboring gene gamma-aminobutyric acid type A receptor subunit beta1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acrosome reaction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptide hormone processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of blood pressure IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
atrial natriuretic peptide-converting enzyme

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056663.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    164098937..164350098
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007075910.3 → XP_007075972.1  atrial natriuretic peptide-converting enzyme isoform X5

    UniProtKB/TrEMBL
    A0A8C9KVT2, A0A8C9L0T2
    Related
    ENSPTIP00000024209.1
    Conserved Domains (7) summary
    cd07445
    Location:138 → 266
    CRD_corin_1; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    cd07888
    Location:457 → 578
    CRD_corin_2; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    smart00020
    Location:804 → 1033
    Tryp_SPc; Trypsin-like serine protease
    cd00112
    Location:272 → 307
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:805 → 1036
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00057
    Location:583 → 617
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    cl02509
    Location:716 → 797
    SRCR_2; Scavenger receptor cysteine-rich domain

  2. XM_042984584.1 → XP_042840518.1  atrial natriuretic peptide-converting enzyme isoform X1

    UniProtKB/TrEMBL
    A0A8C9L0T2
    Conserved Domains (6) summary
    cd07445
    Location:213 → 341
    CRD_corin_1; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    cd07888
    Location:532 → 653
    CRD_corin_2; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    PHA03381
    Location:15 → 103
    PHA03381; tegument protein VP22; Provisional
    smart00202
    Location:768 → 864
    SR; Scavenger receptor Cys-rich
    cd00112
    Location:658 → 692
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:880 → 1111
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  3. XM_042984587.1 → XP_042840521.1  atrial natriuretic peptide-converting enzyme isoform X4

    UniProtKB/TrEMBL
    A0A8C9L0T2
    Conserved Domains (6) summary
    cd07445
    Location:213 → 341
    CRD_corin_1; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    cd07888
    Location:532 → 653
    CRD_corin_2; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    PHA03381
    Location:15 → 103
    PHA03381; tegument protein VP22; Provisional
    smart00202
    Location:731 → 827
    SR; Scavenger receptor Cys-rich
    cd00112
    Location:658 → 692
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:843 → 1074
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  4. XM_042984585.1 → XP_042840519.1  atrial natriuretic peptide-converting enzyme isoform X2

    UniProtKB/TrEMBL
    A0A8C9L0T2
    Conserved Domains (6) summary
    cd07445
    Location:213 → 341
    CRD_corin_1; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    cd07888
    Location:532 → 653
    CRD_corin_2; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    PHA03381
    Location:15 → 103
    PHA03381; tegument protein VP22; Provisional
    smart00202
    Location:732 → 828
    SR; Scavenger receptor Cys-rich
    cd00112
    Location:420 → 455
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:844 → 1075
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  5. XM_042984586.1 → XP_042840520.1  atrial natriuretic peptide-converting enzyme isoform X3

    UniProtKB/TrEMBL
    A0A8C9L0T2
    Conserved Domains (6) summary
    cd07445
    Location:213 → 341
    CRD_corin_1; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    cd07888
    Location:496 → 617
    CRD_corin_2; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    PHA03381
    Location:15 → 103
    PHA03381; tegument protein VP22; Provisional
    smart00202
    Location:732 → 828
    SR; Scavenger receptor Cys-rich
    cd00112
    Location:622 → 656
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:844 → 1075
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

  6. XM_042984588.1 → XP_042840522.1  atrial natriuretic peptide-converting enzyme isoform X6

    UniProtKB/TrEMBL
    A0A8C9L0T2
    Conserved Domains (5) summary
    cd07445
    Location:106 → 234
    CRD_corin_1; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    cd07888
    Location:425 → 546
    CRD_corin_2; One of two cysteine-rich domains of the corin protein, a type II transmembrane serine protease
    smart00202
    Location:661 → 757
    SR; Scavenger receptor Cys-rich
    cd00112
    Location:551 → 585
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00190
    Location:773 → 1004
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.