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MYD88 MYD88 innate immune signal transduction adaptor [ Panthera tigris (tiger) ]

Gene ID: 102952059, updated on 10-Mar-2024

Summary

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Gene symbol
MYD88
Gene description
MYD88 innate immune signal transduction adaptor
See related
Ensembl:ENSPTIG00000011974
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: C2
Exon count:
5
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) C2 NC_056668.1 (151318483..151321980, complement)

Chromosome C2 - NC_056668.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 13 Neighboring gene oxidative stress responsive kinase 1 Neighboring gene elongation factor 1-alpha 1-like Neighboring gene acetyl-CoA acyltransferase 1 Neighboring gene DLEC1 cilia and flagella associated protein Neighboring gene uncharacterized LOC122241992

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056668.1 Chromosome C2 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables TIR domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Toll-like receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in MyD88-dependent toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in Toll signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to Gram-positive bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myeloid differentiation primary response protein MyD88
Names
myeloid differentiation primary response 88

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056668.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    151318483..151321980 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042956247.1 → XP_042812181.1  myeloid differentiation primary response protein MyD88

    UniProtKB/TrEMBL
    A0A8C9JSD3
    Conserved Domains (2) summary
    smart00255
    Location:160 → 296
    TIR; Toll - interleukin 1 - resistance
    cd08312
    Location:29 → 106
    Death_MyD88; Death domain of Myeloid Differentation primary response protein MyD88
Nucleotide Protein
Heading Accession and Version

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