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EIF1B eukaryotic translation initiation factor 1B [ Homo sapiens (human) ]

Gene ID: 10289, updated on 9-Dec-2018

Summary

Official Symbol
EIF1Bprovided by HGNC
Official Full Name
eukaryotic translation initiation factor 1Bprovided by HGNC
Primary source
HGNC:HGNC:30792
See related
Ensembl:ENSG00000114784
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GC20
Expression
Ubiquitous expression in heart (RPKM 113.1), bone marrow (RPKM 72.6) and 25 other tissues See more
Orthologs

Genomic context

See EIF1B in Genome Data Viewer
Location:
3p22.1
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 3 NC_000003.12 (40309682..40312424)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (40351173..40353915)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene myosin VIIA and Rab interacting protein Neighboring gene uncharacterized LOC105377645 Neighboring gene EIF1B antisense RNA 1 Neighboring gene RNA, 7SL, cytoplasmic 411, pseudogene Neighboring gene phosphoglycerate mutase 1 pseudogene 3 Neighboring gene ENTPD3 antisense RNA 1 Neighboring gene ectonucleoside triphosphate diphosphohydrolase 3

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from BioSystems

  • RNA transport, organism-specific biosystem (from KEGG)
    RNA transport, organism-specific biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
  • RNA transport, conserved biosystem (from KEGG)
    RNA transport, conserved biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ribosomal small subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
translation initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
regulation of translational initiation NAS
Non-traceable Author Statement
more info
PubMed 
translational initiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
eukaryotic 43S preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
eukaryotic translation initiation factor 1b
Names
protein translation factor SUI1 homolog GC20
translation factor sui1 homolog

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005875.3NP_005866.1  eukaryotic translation initiation factor 1b

    See identical proteins and their annotated locations for NP_005866.1

    Status: VALIDATED

    Source sequence(s)
    AA521449, BC006996
    Consensus CDS
    CCDS2690.1
    UniProtKB/Swiss-Prot
    O60739
    UniProtKB/TrEMBL
    Q6FG85
    Related
    ENSP00000232905.3, ENST00000232905.3
    Conserved Domains (1) summary
    cl00229
    Location:4113
    eIF1_SUI1_like; Eukaryotic initiation factor 1 and related proteins

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p12 Primary Assembly

    Range
    40309682..40312424
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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