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LINC01315 long intergenic non-protein coding RNA 1315 [ Homo sapiens (human) ]

Gene ID: 102723775, updated on 25-Nov-2025
Official Symbol
LINC01315provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1315provided by HGNC
Primary source
HGNC:HGNC:50513
See related
Ensembl:ENSG00000229891 AllianceGenome:HGNC:50513
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C22orf32-1; lnc-C22orf32-1
Expression
Broad expression in thyroid (RPKM 6.7), skin (RPKM 2.3) and 15 other tissues See more
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See LINC01315 in Genome Data Viewer
Location:
22q13.2
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (42364400..42369208, complement)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (42845402..42850211, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (42760406..42765214, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene ccytochrome P450 family 2 subfamily D member 8, pseudogene Neighboring gene transcription factor 20 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42610989-42611488 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr22:42613759-42614347 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19154 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19155 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13820 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13821 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13822 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13823 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42670872-42671668 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr22:42671669-42672465 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19156 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42678224-42679074 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42679075-42679924 Neighboring gene opioid growth factor receptor pseudogene 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42690639-42691452 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42693767-42694412 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42695786-42696464 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42696465-42697143 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42697144-42697822 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42706428-42707134 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42709047-42709876 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42710708-42711537 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42714279-42715176 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42716129-42716966 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42721410-42722037 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42734449-42735057 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42735333-42735954 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42735955-42736576 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42747603-42748103 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19160 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42759143-42759796 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42761307-42762149 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:42763534-42764468 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19161 Neighboring gene Sharpr-MPRA regulatory region 6115 Neighboring gene uncharacterized LOC124905126 Neighboring gene Sharpr-MPRA regulatory region 1538 Neighboring gene NFAT activating protein with ITAM motif 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19162 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:42821196-42821779 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19163

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. LINC01315 accelerates the growth and epithelial-mesenchymal transition of colorectal cancer cells via activating the Wnt/β-catenin signal. Liu Y, et al. Bioengineered, 2022 Apr. PMID 35322763, Free PMC Article
  2. LncRNA LINC01315 silencing modulates cancer stem cell properties and epithelial-to-mesenchymal transition in colorectal cancer via miR-484/DLK1 axis. Li Y, et al. Cell Cycle, 2022 Apr. PMID 35156543, Free PMC Article
  3. lncRNA C22orf32-1 contributes to the tumorigenesis of nasopharyngeal carcinoma. Nie GH, et al. Oncol Lett, 2017 Jun. PMID 28588717, Free PMC Article
  4. LINC01315 promotes the aggressive phenotypes of papillary thyroid cancer cells by sponging miR-497-5p. Ren J, et al. Kaohsiung J Med Sci, 2021 Jun. PMID 33611825, Free PMC Article
  5. LINC01315 silencing inhibits the aggressive phenotypes of colorectal carcinoma by sponging miR-205-3p. Liang R, et al. Biochem Biophys Res Commun, 2021 Jan 1. PMID 33162032

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LINC01315 accelerates the growth and epithelial-mesenchymal transition of colorectal cancer cells via activating the Wnt/beta-catenin signal.
    Title: LINC01315 accelerates the growth and epithelial-mesenchymal transition of colorectal cancer cells via activating the Wnt/β-catenin signal.
  2. lncRNA LINC01315 promotes malignancy of triple-negative breast cancer and predicts poor outcomes by modulating microRNA-876-5p/GRK5.
    Title: lncRNA LINC01315 promotes malignancy of triple-negative breast cancer and predicts poor outcomes by modulating microRNA-876-5p/GRK5.
  3. LncRNA LINC01315 silencing modulates cancer stem cell properties and epithelial-to-mesenchymal transition in colorectal cancer via miR-484/DLK1 axis.
    Title: LncRNA LINC01315 silencing modulates cancer stem cell properties and epithelial-to-mesenchymal transition in colorectal cancer via miR-484/DLK1 axis.
  4. LINC01315 promotes the aggressive phenotypes of papillary thyroid cancer cells by sponging miR-497-5p.
    Title: LINC01315 promotes the aggressive phenotypes of papillary thyroid cancer cells by sponging miR-497-5p.
  5. LINC01315 silencing inhibits the aggressive phenotypes of colorectal carcinoma by sponging miR-205-3p.
    Title: LINC01315 silencing inhibits the aggressive phenotypes of colorectal carcinoma by sponging miR-205-3p.
Submit: New GeneRIF Correction

Review eQTL and phenotype association data in this region using PheGenI

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_120595.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AI914073, BC038245, CB050274
    Related
    ENST00000669665.3

  2. NR_120596.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' exon, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AI914073, AV709904, BC038245, CB050274
    Related
    ENST00000432473.4

  3. NR_120597.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses alternate splice sites at the 5' and 3' exons, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AI914073, CB050274
    Related
    ENST00000412060.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    42364400..42369208 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    42845402..42850211 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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