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Acad11 acyl-Coenzyme A dehydrogenase family, member 11 [ Mus musculus (house mouse) ]

Gene ID: 102632, updated on 18-Apr-2024

Summary

Official Symbol
Acad11provided by MGI
Official Full Name
acyl-Coenzyme A dehydrogenase family, member 11provided by MGI
Primary source
MGI:MGI:2143169
See related
Ensembl:ENSMUSG00000090150 AllianceGenome:MGI:2143169
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5730439E10Rik
Summary
Predicted to enable medium-chain-acyl-CoA dehydrogenase activity and very-long-chain-acyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to act upstream of or within fatty acid metabolic process. Located in mitochondrion. Is expressed in central nervous system and retina. Orthologous to human ACAD11 (acyl-CoA dehydrogenase family member 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in liver adult (RPKM 65.5), kidney adult (RPKM 50.8) and 23 other tissues See more
Orthologs
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Genomic context

Location:
9 F1; 9 56.25 cM
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (103940923..104004855)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (104063724..104127656)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene NSA2 ribosome biogenesis homolog pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr9:103965595-103965778 Neighboring gene STARR-seq mESC enhancer starr_25105 Neighboring gene ubiquitin-like modifier activating enzyme 5 Neighboring gene STARR-seq mESC enhancer starr_25106 Neighboring gene atypical chemokine receptor 4 Neighboring gene STARR-seq mESC enhancer starr_25110 Neighboring gene DnaJ heat shock protein family (Hsp40) member C13 Neighboring gene high mobility group box 1, related sequence 16 Neighboring gene predicted gene, 46130

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 
  • Gene trapped (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: Nphp3

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acyl-CoA dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables long-chain fatty acyl-CoA dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
enables medium-chain fatty acyl-CoA dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-CH group of donors IEA
Inferred from Electronic Annotation
more info
 
enables very-long-chain fatty acyl-CoA dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
acyl-CoA dehydrogenase family member 11
NP_780533.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175324.4NP_780533.2  acyl-CoA dehydrogenase family member 11

    See identical proteins and their annotated locations for NP_780533.2

    Status: VALIDATED

    Source sequence(s)
    AI843434, AK077531
    Consensus CDS
    CCDS23458.1
    UniProtKB/Swiss-Prot
    Q80XL6, Q8BK19
    UniProtKB/TrEMBL
    A0A0R4J0I6
    Related
    ENSMUSP00000043424.6, ENSMUST00000047799.13
    Conserved Domains (3) summary
    cd01155
    Location:376769
    ACAD_FadE2; Acyl-CoA dehydrogenases similar to fadE2
    PLN02876
    Location:6769
    PLN02876; acyl-CoA dehydrogenase
    cd05154
    Location:42292
    ACAD10_11_N-like; N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    103940923..104004855
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)