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MIR7850 microRNA 7850 [ Homo sapiens (human) ]

Gene ID: 102465838, updated on 4-Mar-2025

Summary

Official Symbol
MIR7850provided by HGNC
Official Full Name
microRNA 7850provided by HGNC
Primary source
HGNC:HGNC:50118
See related
Ensembl:ENSG00000277904 miRBase:MI0025520; AllianceGenome:HGNC:50118
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
hsa-mir-7850
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

See MIR7850 in Genome Data Viewer
Location:
19p13.3
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (2630715..2630793)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (2606978..2607056)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (2630713..2630791)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene G protein subunit gamma 7 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2540747-2541566 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2541567-2542386 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2543207-2544026 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2544027-2544846 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2544847-2545665 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13702 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2546759-2547703 Neighboring gene elongin C pseudogene 28 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2556671-2557284 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:2559714-2560214 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13703 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2567191-2567718 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2567719-2568246 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:2575316-2575816 Neighboring gene HNF4 motif-containing MPRA enhancer 50 Neighboring gene Sharpr-MPRA regulatory region 4130 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2587299-2588242 Neighboring gene H3K27ac hESC enhancer GRCh37_chr19:2592455-2592956 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:2603289-2604055 Neighboring gene RNA, 7SL, cytoplasmic 121, pseudogene Neighboring gene H3K4me1 hESC enhancers GRCh37_chr19:2607315-2608169 and GRCh37_chr19:2608170-2609023 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13707 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9803 Neighboring gene Sharpr-MPRA regulatory region 3019 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13708 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13709 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13710 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr19:2626979-2628178 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13711 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:2643435-2643934 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:2650512-2650687 Neighboring gene GNG7 intron CAGE-defined B cell enhancer Neighboring gene MPRA-validated peak3237 silencer Neighboring gene ReSE screen-validated silencer GRCh37_chr19:2678080-2678228 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13713 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9804 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13714 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:2723575-2724487 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13715 Neighboring gene DIRAS family GTPase 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:2734868-2735368 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:2735369-2735869 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:2739111-2739378 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13716 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9805 Neighboring gene solute carrier family 39 member 3

Genomic regions, transcripts, and products

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_107004.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC092068
    Related
    ENST00000618087.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    2630715..2630793
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    2606978..2607056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)