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DDX58 DExD/H-box helicase 58 [ Pelodiscus sinensis (Chinese soft-shelled turtle) ]

Gene ID: 102452744, updated on 16-Nov-2018

Summary

Gene symbol
DDX58
Gene description
DExD/H-box helicase 58
See related
Ensembl:ENSPSIG00000013490
Gene type
protein coding
RefSeq status
MODEL
Organism
Pelodiscus sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudines; Cryptodira; Trionychia; Trionychidae; Pelodiscus
Orthologs

Genomic context

See DDX58 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
102 current PelSin_1.0 (GCF_000230535.1) Unplaced Scaffold NW_005855220.1 (1865924..1905043, complement)

NW_005855220.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112545794 Neighboring gene uncharacterized LOC112545795 Neighboring gene aconitase 1

Genomic regions, transcripts, and products

Genomic Sequence:
NW_005855220 Unplaced Scaffold Reference PelSin_1.0 Primary Assembly

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Cytosolic DNA-sensing pathway, organism-specific biosystem (from KEGG)
    Cytosolic DNA-sensing pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting foreign DNA from invading microbes or host cells and generating innate immune responses. DAI is the first identified s...
  • Cytosolic DNA-sensing pathway, conserved biosystem (from KEGG)
    Cytosolic DNA-sensing pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting foreign DNA from invading microbes or host cells and generating innate immune responses. DAI is the first identified s...
  • Herpes simplex infection, organism-specific biosystem (from KEGG)
    Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • Herpes simplex infection, conserved biosystem (from KEGG)
    Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • RIG-I-like receptor signaling pathway, organism-specific biosystem (from KEGG)
    RIG-I-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular ...
  • RIG-I-like receptor signaling pathway, conserved biosystem (from KEGG)
    RIG-I-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular ...

General protein information

Preferred Names
probable ATP-dependent RNA helicase DDX58

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Pelodiscus sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PelSin_1.0 Primary Assembly

Genomic

  1. NW_005855220.1 Reference PelSin_1.0 Primary Assembly

    Range
    1865924..1905043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014573634.2XP_014429120.1  probable ATP-dependent RNA helicase DDX58 isoform X2

    Conserved Domains (7) summary
    COG1111
    Location:235785
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    cd00046
    Location:256408
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd08816
    Location:290
    CARD_RIG-I_r1; Caspase activation and recruitment domain found in RIG-I, first repeat
    cd08817
    Location:98187
    CARD_RIG-I_r2; Caspase activation and recruitment domain found in RIG-I, second repeat
    cd15805
    Location:803917
    RIG-I_C; C-terminal domain of Retinoic acid-inducible gene (RIG)-I protein, a cytoplasmic viral RNA receptor
    cl17041
    Location:469601
    helicase_insert_domain; helicase_insert_domain
    pfam00271
    Location:614731
    Helicase_C; Helicase conserved C-terminal domain
  2. XM_006123090.3XP_006123152.1  probable ATP-dependent RNA helicase DDX58 isoform X1

    UniProtKB/TrEMBL
    K7G5C6
    Related
    ENSPSIP00000015487.1, ENSPSIT00000015560.1
    Conserved Domains (7) summary
    COG1111
    Location:236786
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    cd00046
    Location:257409
    DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
    cd08816
    Location:290
    CARD_RIG-I_r1; Caspase activation and recruitment domain found in RIG-I, first repeat
    cd08817
    Location:98187
    CARD_RIG-I_r2; Caspase activation and recruitment domain found in RIG-I, second repeat
    cd15805
    Location:804918
    RIG-I_C; C-terminal domain of Retinoic acid-inducible gene (RIG)-I protein, a cytoplasmic viral RNA receptor
    cl17041
    Location:470602
    helicase_insert_domain; helicase_insert_domain
    pfam00271
    Location:615732
    Helicase_C; Helicase conserved C-terminal domain
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