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Xylb xylulokinase homolog (H. influenzae) [ Mus musculus (house mouse) ]

Gene ID: 102448, updated on 9-May-2024

Summary

Official Symbol
Xylbprovided by MGI
Official Full Name
xylulokinase homolog (H. influenzae)provided by MGI
Primary source
MGI:MGI:2142985
See related
Ensembl:ENSMUSG00000035769 AllianceGenome:MGI:2142985
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable xylulokinase activity. Predicted to be involved in phosphorylation and xylulose metabolic process. Predicted to be active in cytosol. Orthologous to human XYLB (xylulokinase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney adult (RPKM 57.9), liver adult (RPKM 23.4) and 1 other tissue See more
Orthologs
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Genomic context

See Xylb in Genome Data Viewer
Location:
9 F3; 9 71.33 cM
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (119186447..119222863)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (119357381..119393797)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E11425 Neighboring gene myeloid differentiation primary response gene 88 Neighboring gene acetyl-Coenzyme A acyltransferase 1A Neighboring gene predicted gene, 53515 Neighboring gene activin receptor IIB

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables D-xylulokinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables D-xylulokinase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
xylulose kinase
NP_001028381.1
NP_001186497.1
NP_001346628.1
XP_030099799.1
XP_030099800.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033209.3NP_001028381.1  xylulose kinase isoform 1

    See identical proteins and their annotated locations for NP_001028381.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer protein (isoform 1).
    Source sequence(s)
    AK143476, AK165759
    Consensus CDS
    CCDS23614.1
    UniProtKB/Swiss-Prot
    B2RR66, Q3TNA1, Q8R156
    UniProtKB/TrEMBL
    Q66JV3
    Related
    ENSMUSP00000047254.9, ENSMUST00000039610.10
    Conserved Domains (2) summary
    PLN02669
    Location:26549
    PLN02669; xylulokinase
    cd07776
    Location:24494
    FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases
  2. NM_001199568.1NP_001186497.1  xylulose kinase isoform 2

    See identical proteins and their annotated locations for NP_001186497.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has multiple differences, one of which results in the use of a downstream start codon, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.
    Source sequence(s)
    AK143476, AK164186, AK165759
    UniProtKB/TrEMBL
    Q3TMS3
    Conserved Domains (1) summary
    cl17037
    Location:1261
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
  3. NM_001359699.1NP_001346628.1  xylulose kinase isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks a 5' exon which results in the use of a downstream start codon, compared to variant 1. The resulting protein (isoform 3) is shorter when it is compared to isoform 1.
    Source sequence(s)
    AC128702, AC166052
    UniProtKB/TrEMBL
    Q66JV3
    Conserved Domains (1) summary
    cd07776
    Location:1401
    FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    119186447..119222863
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030243939.1XP_030099799.1  xylulose kinase isoform X1

    UniProtKB/TrEMBL
    Q66JV3
    Conserved Domains (1) summary
    cd07776
    Location:1401
    FGGY_D-XK_euk; eukaryotic D-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases
  2. XM_030243940.1XP_030099800.1  xylulose kinase isoform X2

    UniProtKB/TrEMBL
    Q3TMS3
    Related
    ENSMUST00000213383.2
    Conserved Domains (1) summary
    cl17037
    Location:1261
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily