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BRAF B-Raf proto-oncogene, serine/threonine kinase [ Bos mutus (wild yak) ]

Gene ID: 102278631, updated on 10-Mar-2024

Summary

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Gene symbol
BRAF
Gene description
B-Raf proto-oncogene, serine/threonine kinase
Locus tag
M91_13144
See related
Ensembl:ENSBMUG00000014190
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos mutus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
101 current BosGru_v2.0 (GCF_000298355.1) Unplaced Scaffold NW_005394292.1 (1106760..1211673)

NW_005394292.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 178B Neighboring gene 40S ribosomal protein S10 pseudogene Neighboring gene mitochondrial ribosomal protein S33 Neighboring gene NADH:ubiquinone oxidoreductase subunit B2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005394292.1 Unplaced Scaffold Reference BosGru_v2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase B-raf
Names
Serine/threonine-protein kinase B-raf
v-raf murine sarcoma viral oncogene homolog B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos mutus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BosGru_v2.0 Primary Assembly

Genomic

  1. NW_005394292.1 Reference BosGru_v2.0 Primary Assembly

    Range
    1106760..1211673
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005901074.2 → XP_005901136.1  serine/threonine-protein kinase B-raf

    UniProtKB/TrEMBL
    L8I8L7
    Related
    ENSBMUP00000019100.1, ENSBMUT00000022091.1
    Conserved Domains (4) summary
    cd01816
    Location:166 → 237
    Raf_RBD; Ubiquitin domain of Raf serine/threonine kinases
    cd14062
    Location:513 → 756
    STKc_Raf; Catalytic domain of the Serine/Threonine Kinases, Raf (Rapidly Accelerated Fibrosarcoma) kinases
    pfam00130
    Location:245 → 290
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam07714
    Location:507 → 755
    Pkinase_Tyr; Protein tyrosine kinase
Nucleotide Protein
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