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LINC01108 long intergenic non-protein coding RNA 1108 [ Homo sapiens (human) ]

Gene ID: 102216342, updated on 3-Mar-2026
Official Symbol
LINC01108provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 1108provided by HGNC
Primary source
HGNC:HGNC:49234
See related
Ensembl:ENSG00000226673 AllianceGenome:HGNC:49234
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LncRNA-ES1
Expression
Low expression observed in reference dataset See more
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Try the new Transcripts and proteins table
See LINC01108 in Genome Data Viewer
Location:
6p23
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (14280127..14285454, complement)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (14152651..14157970, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (14280358..14285685, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene RNA, U7 small nuclear 133 pseudogene Neighboring gene MPRA-validated peak5669 silencer Neighboring gene uncharacterized LOC105374940 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16943 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16944 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24049 Neighboring gene MPRA-validated peak5670 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:14235700-14236200 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:14236201-14236701 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24050 Neighboring gene NANOG hESC enhancer GRCh37_chr6:14265410-14265941 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr6:14270712-14271911 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr6:14273182-14274095 Neighboring gene uncharacterized LOC124901266 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:14297089-14297757 Neighboring gene H3K27ac hESC enhancer GRCh37_chr6:14298956-14299481 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr6:14301988-14302627 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:14302628-14303268 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr6:14330461-14330962 Neighboring gene Sharpr-MPRA regulatory region 8710 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:14381289-14381830 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr6:14381831-14382374 Neighboring gene uncharacterized LOC105374943

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. Long non-coding RNA ENST01108 promotes carcinogenesis of glioma by acting as a molecular sponge to modulate miR-489. Xu D, et al. Biomed Pharmacother, 2018 Apr. PMID 29421578
  2. Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors. Ng SY, et al. EMBO J, 2012 Feb 1. PMID 22193719, Free PMC Article
  3. Intergenic variants may predispose to major depression disorder through regulation of long non-coding RNA expression. Ye N, et al. Gene, 2017 Feb 15. PMID 27940106
  4. VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Yue Y, et al. Cell Discov, 2018. PMID 29507755, Free PMC Article
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039

GeneRIFs: Gene References Into Functions

Review eQTL and phenotype association data in this region using PheGenI

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

Products Interactant Other Gene Complex Source Pubs Description

Other Names

  • lncrna embryonic stem cell 1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_108096.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AL353152

  2. NR_108097.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal exon, resulting in a shorter transcript, compared to variant 1.
    Source sequence(s)
    AL353152
    Related
    ENST00000427276.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    14280127..14285454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    14152651..14157970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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