U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CYLD CYLD lysine 63 deubiquitinase [ Capra hircus (goat) ]

Gene ID: 102179035, updated on 10-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
CYLD
Gene description
CYLD lysine 63 deubiquitinase
See related
EnsemblRapid:ENSCHIG00000026390
Gene type
protein coding
RefSeq status
MODEL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CYLD in Genome Data Viewer
Location:
chromosome: 18
Exon count:
20
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 18 NC_030825.1 (18113247..18180385, complement)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 18 NC_022310.1 (18583093..18655583)

Chromosome 18 - NC_030825.1Genomic Context describing neighboring genes Neighboring gene spalt like transcription factor 1 Neighboring gene protein ABHD18 pseudogene Neighboring gene nucleotide binding oligomerization domain containing 2 Neighboring gene sorting nexin 20

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables K63-linked deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in necroptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of extrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of intrinsic apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
ubiquitin carboxyl-terminal hydrolase CYLD

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030825.1 Reference ASM170441v1 Primary Assembly

    Range
    18113247..18180385 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018061937.1 → XP_017917426.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X2

    UniProtKB/TrEMBL
    A0A8C2REF1

  2. XM_018061934.1 → XP_017917423.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X1

    UniProtKB/TrEMBL
    A0A452G7G4, A0A8C2REF1
    Conserved Domains (3) summary
    smart01052
    Location:469 → 537
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    cd02670
    Location:590 → 945
    Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam16607
    Location:304 → 468
    CYLD_phos_site; Phosphorylation region of CYLD, unstructured

  3. XM_018061935.1 → XP_017917424.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X1

    UniProtKB/TrEMBL
    A0A452G7G4, A0A8C2REF1
    Conserved Domains (3) summary
    smart01052
    Location:469 → 537
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    cd02670
    Location:590 → 945
    Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam16607
    Location:304 → 468
    CYLD_phos_site; Phosphorylation region of CYLD, unstructured

  4. XM_018061938.1 → XP_017917427.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X3

    Related
    ENSCHIP00000032405.2, ENSCHIT00000040280.2
    Conserved Domains (3) summary
    smart01052
    Location:247 → 315
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    cd02670
    Location:368 → 723
    Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam16607
    Location:82 → 246
    CYLD_phos_site; Phosphorylation region of CYLD, unstructured

  5. XM_018061936.1 → XP_017917425.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X1

    UniProtKB/TrEMBL
    A0A452G7G4, A0A8C2REF1
    Conserved Domains (3) summary
    smart01052
    Location:469 → 537
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    cd02670
    Location:590 → 945
    Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam16607
    Location:304 → 468
    CYLD_phos_site; Phosphorylation region of CYLD, unstructured

  6. XM_013971026.2 → XP_013826480.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform X1

    UniProtKB/TrEMBL
    A0A452G7G4, A0A8C2REF1
    Related
    ENSCHIP00000032426.1, ENSCHIT00000040301.2
    Conserved Domains (3) summary
    smart01052
    Location:469 → 537
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    cd02670
    Location:590 → 945
    Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam16607
    Location:304 → 468
    CYLD_phos_site; Phosphorylation region of CYLD, unstructured
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.