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Kndc1 kinase non-catalytic C-lobe domain containing 1 [ Ictidomys tridecemlineatus (thirteen-lined ground squirrel) ]

Gene ID: 101970226, updated on 8-Mar-2024

Summary

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Gene symbol
Kndc1
Gene description
kinase non-catalytic C-lobe domain containing 1
Locus tag
H1C71_000083
Gene type
protein coding
RefSeq status
MODEL
Organism
Ictidomys tridecemlineatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
30
Annotation release Status Assembly Chr Location
103 current HiC_Itri_2 (GCF_016881025.1) Unplaced Scaffold NW_024407213.1 (6220171..6273828, complement)
102 previous assembly SpeTri2.0 (GCF_000236235.1) Unplaced Scaffold NW_004936486.1 (19287468..19341127)

NW_024407213.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120885801 Neighboring gene uncharacterized LOC120885861 Neighboring gene undifferentiated embryonic cell transcription factor 1 Neighboring gene uncharacterized LOC120885862 Neighboring gene adhesion G protein-coupled receptor A1 Neighboring gene uncharacterized LOC110597723

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
kinase non-catalytic C-lobe domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ictidomys tridecemlineatus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HiC_Itri_2 Primary Assembly

Genomic

  1. NW_024407213.1 Reference HiC_Itri_2 Primary Assembly

    Range
    6220171..6273828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021723411.2 → XP_021579086.1  kinase non-catalytic C-lobe domain-containing protein 1 isoform X2

    Conserved Domains (5) summary
    cd06224
    Location:1262 → 1361
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    PHA03247
    Location:640 → 893
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:734 → 1097
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam00617
    Location:1483 → 1614
    RasGEF; RasGEF domain
    cl21453
    Location:36 → 214
    PKc_like; Protein Kinases, catalytic domain

  2. XM_021723412.2 → XP_021579087.1  kinase non-catalytic C-lobe domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    I3M250
    Conserved Domains (5) summary
    cd06224
    Location:1247 → 1346
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    PHA03307
    Location:719 → 1082
    PHA03307; transcriptional regulator ICP4; Provisional
    PRK07764
    Location:674 → 891
    PRK07764; DNA polymerase III subunits gamma and tau; Validated
    pfam00617
    Location:1468 → 1612
    RasGEF; RasGEF domain
    cl21453
    Location:36 → 214
    PKc_like; Protein Kinases, catalytic domain

  3. XM_040273674.1 → XP_040129608.1  kinase non-catalytic C-lobe domain-containing protein 1 isoform X4

    Conserved Domains (4) summary
    cd06224
    Location:1159 → 1258
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    PHA03247
    Location:640 → 893
    PHA03247; large tegument protein UL36; Provisional
    cl02485
    Location:1369 → 1605
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cl21453
    Location:36 → 214
    PKc_like; Protein Kinases, catalytic domain

  4. XM_021723410.2 → XP_021579085.1  kinase non-catalytic C-lobe domain-containing protein 1 isoform X1

    Conserved Domains (5) summary
    cd06224
    Location:1262 → 1361
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    PHA03247
    Location:640 → 893
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:734 → 1097
    PHA03307; transcriptional regulator ICP4; Provisional
    pfam00617
    Location:1483 → 1627
    RasGEF; RasGEF domain
    cl21453
    Location:36 → 214
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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