U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HSFX3 heat shock transcription factor family, X-linked member 3 [ Homo sapiens (human) ]

Gene ID: 101928917, updated on 13-May-2022

Summary

Official Symbol
HSFX3provided by HGNC
Official Full Name
heat shock transcription factor family, X-linked member 3provided by HGNC
Primary source
HGNC:HGNC:52395
See related
Ensembl:ENSG00000283697 AllianceGenome:HGNC:52395
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 12.8), adrenal (RPKM 9.1) and 23 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See HSFX3 in Genome Data Viewer
Location:
Xq28
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (149548210..149549924, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (147813976..147815690, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (148629755..148631469, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene IDSP1 recombination region Neighboring gene EOLA1 divergent transcript Neighboring gene iduronate 2-sulfatase pseudogene 1 Neighboring gene endothelium and lymphocyte associated ASCH domain 1 Neighboring gene MAGE family member A9B Neighboring gene heat shock transcription factor family, X-linked 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in chromatin ISA
Inferred from Sequence Alignment
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
heat shock transcription factor, X-linked member 3
Names
heat shock transcription factor, X-linked-like

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001323079.3NP_001310008.1  heat shock transcription factor, X-linked member 3

    Status: VALIDATED

    Source sequence(s)
    AC244197
    Consensus CDS
    CCDS83499.1
    UniProtKB/Swiss-Prot
    A0A1B0GWH4
    Related
    ENSP00000490928.1, ENST00000431993.4
    Conserved Domains (1) summary
    pfam00447
    Location:83182
    HSF_DNA-bind; HSF-type DNA-binding

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    149548210..149549924 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    147813976..147815690 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)