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BEST1 bestrophin 1 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 101925702, updated on 26-Jun-2025
Gene symbol
BEST1
Gene description
bestrophin 1
See related
Ensembl:ENSMFAG00000033154
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
VMD2; bestrophin
Orthologs
all
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Try the new Transcripts and proteins table
See BEST1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2025_03 current T2T-MFA8v1.1 (GCF_037993035.2) 14 NC_088388.1 (12022181..12038126, complement)

Chromosome 14 - NC_088388.1Genomic Context describing neighboring genes Neighboring gene inner centromere protein Neighboring gene ferritin heavy chain 1 Neighboring gene RAB3A interacting protein like 1 Neighboring gene fatty acid desaturase 3

Genomic Sequence:
NC_088388.1 Chromosome 14 Reference T2T-MFA8v1.1

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chloride channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
bestrophin-1
Names
Bestrophin-1
Vitelliform macular dystrophy protein 2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_037993035.2-RS_2025_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MFA8v1.1

Genomic

  1. NC_088388.1 Reference T2T-MFA8v1.1

    Range
    12022181..12038126 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_074013430.1 → XP_073869531.1  bestrophin-1 isoform X6

  2. XM_015434136.4 → XP_015289622.2  bestrophin-1 isoform X2

    UniProtKB/TrEMBL
    A0A2K5V6M8
    Conserved Domains (1) summary
    pfam01062
    Location:9 → 290
    Bestrophin; RFP-TM, chloride channel

  3. XM_074013429.1 → XP_073869530.1  bestrophin-1 isoform X5

  4. XM_005577603.5 → XP_005577660.2  bestrophin-1 isoform X1

    UniProtKB/Swiss-Prot
    Q4R348, Q6UY87
    UniProtKB/TrEMBL
    A0A2K5V6P4
    Conserved Domains (1) summary
    pfam01062
    Location:9 → 316
    Bestrophin; RFP-TM, chloride channel

  5. XM_074013428.1 → XP_073869529.1  bestrophin-1 isoform X4

    UniProtKB/TrEMBL
    A0A2K5V6M8

  6. XM_045371982.3 → XP_045227917.1  bestrophin-1 isoform X3

    UniProtKB/TrEMBL
    A0A2K5V6P4

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001283581.1: Suppressed sequence

    Description
    NM_001283581.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact info@ncbi.nlm.nih.gov for further information.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6UY87.1 GenPept UniProtKB/Swiss-Prot:Q6UY87

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